Gene test could prevent severe chemo side effects

NCT ID NCT07158164

First seen Nov 01, 2025 · Last updated May 06, 2026 · Updated 25 times

Summary

This study looks at whether adjusting the dose of chemotherapy drugs (5-FU or capecitabine) based on a person's DPYD gene test can reduce severe side effects. About 100 adults with certain cancers (like colorectal, breast, or head/neck) will take part. The goal is to see if personalized dosing leads to fewer hospitalizations or life-threatening reactions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Center Initiative

    RECRUITING

    Newark, New Jersey, 07103, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cooperman Barnabas Medical Center

    RECRUITING

    Livingston, New Jersey, 07039, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jack and Sheryl Morris Cancer Center

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • RWJBarnabas Health - Community Medical Center

    RECRUITING

    Toms River, New Jersey, 08755, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • RWJBarnabas Health - Robert Wood Johnson University Hospita

    RECRUITING

    New Brunswick, New Jersey, 08903, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • RWJBarnabas Health - Robert Wood Johnson University Hospital Somerset

    RECRUITING

    Somerville, New Jersey, 08873, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • RWJBarnabas Health - Robert Wood Johnson University Hospital, Hamilton

    RECRUITING

    Hamilton, New Jersey, 08690, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • RWJBarnabas Health Clara Maas Medical Center

    RECRUITING

    Belleville, New Jersey, 07109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • RWJBarnabas Health Jersey City Medical Center

    RECRUITING

    Jersey City, New Jersey, 07302, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • RWJBarnabas Health Newark Beth Israel Medical Center

    RECRUITING

    Newark, New Jersey, 07112, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Trinitas Hospital and Comprehensive Cancer Center

    RECRUITING

    Elizabeth, New Jersey, 07202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital

    RECRUITING

    Newark, New Jersey, 07103, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.