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Daily exercise may ease radiation side effects for head and neck cancer patients

NCT ID NCT05432297

Symptom relief Sponsor: Sahlgrenska University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a daily physical activity routine, started before and continued during radiotherapy, can improve physical function and quality of life for head and neck cancer patients. 80 patients with tumors of the oropharynx, larynx, or hypopharynx will be randomly assigned to either an exercise group or a control group. All patients will have weekly check-ins with a speech therapist or physical therapist.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
daily physical exercise
What this could lead to
If it works, this could show that simple daily exercise helps head and neck cancer patients feel better and stay active during radiation treatment.
What could go wrong
This is a small, early-stage study with only 80 participants. The exercise plan is tailored to each person's daily condition, so results may vary and might not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2023

Expected to finish

Dec 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Head and neck cancer (tumors of the oropharynx, pharynx, hypopharynx and larynx) * Receiving radiohterapy (+/- chemotherapy) with curative intent Exclusion Criteria: * Surgery due to head and neck cancer * Previous treatment for head and neck cancer * Tracheostomized patients * Inability to perform exercise intervention * Inability to perform part of 6-minute walking test * Inability to independently fill out questionnaires in Swedish * Previous neurologic or neuromuscular disease

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Conditions

The condition(s) this trial relates to.

head and neck cancer head and neck neoplasm Head and Neck Neoplasms hypopharyngeal carcinoma laryngeal carcinoma oropharyngeal carcinoma Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Head and neck neoplasms Physical inactivity

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sahlgrenska University Hospital

    RECRUITING

    Gothenburg, 41345, Sweden

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