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Can a mindset therapy boost exercise in people with low mood?

NCT ID NCT05407935

Symptom relief Sponsor: Brown University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 03, 2026 · Last updated Sep 04, 2026 · Updated 1 time

Summary

This trial tests whether a program called ACTivity, which uses acceptance and commitment therapy to encourage physical activity, can help low-active adults with depressive symptoms become more active. Participants are randomly assigned to either ACTivity or a relaxation-based comparison program, both including goal-setting and self-monitoring. They attend weekly virtual sessions for 8 weeks and are followed for 6 months, with a YMCA membership provided to both groups. The study measures physical activity levels and depressive symptoms to see if the approach is feasible and promising.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Acceptance and commitment therapy (ACT) combined with standard physical activity promotion strategies, compared to relaxation training with the same strategies
What this could lead to
If it works, this could point toward a practical, group-based program that helps people with depressive symptoms become more physically active, potentially easing their mood.
What could go wrong
This is an early feasibility trial with a small number of participants, so it may not show clear benefits. The program requires weekly virtual sessions, and results may not apply to everyone with depressive symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

75 people

The number who actually took part.

Started

Aug 2022

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Elevated depressive symptoms (CES-D score of greater than or equal to 10) * Low-active (less than 60 minutes per week of moderate intensity PA) * Willing and able to attend weekly virtual video sessions via Zoom Exclusion Criteria: * Regular mindfulness meditation practice (more than once per week) * Body Mass Index (BMI) less than 18.5 or greater than 40 * History or presence of any condition that may limit or substantially increase the risks of physical activity * Active suicidal thoughts or behaviors * Currently participating in any exercise or weight-loss research studies * Household member is participating in this study * Does not have a Rhode Island mailing address OR if only Rhode Island mailing address is a PO box * Unable to receive materials in the mail at residential mailing address * Does not plan to live in Rhode Island for the next 6 months * Unable to speak, read, and/or write fluently in English

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Conditions

The condition(s) this trial relates to.

Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Physical inactivity

Contacts and locations

Locations

  • Brown University

    Providence, Rhode Island, 02912, United States

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Other studies related to the condition(s) this trial covers.