Does Self-Paced walking beat prescribed workouts for midlife health?

NCT ID NCT05285748

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

This trial tests whether telling inactive adults aged 50-64 to exercise at their own chosen pace leads to more physical activity than prescribing a specific moderate intensity. Participants receive a walking-focused exercise plan and a program to help them overcome barriers. Researchers track activity levels, body weight, and other measures over 12 months to see which approach works better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Behavioral intervention: self-paced physical activity versus prescribed moderate-intensity physical activity, both with a walking-focused exercise prescription and a theory-based promotion program.
What this could lead to
If self-paced exercise works better, it could offer a simpler, more sustainable way to help inactive midlife adults become more active and improve their health.
What could go wrong
The trial is relatively small and measures behavior change over a year, so results may not apply broadly. Participants might not stick with the program, and self-paced activity may not match the benefits of moderate intensity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

258 people

The number who actually took part.

Started

Mar 2022

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 64 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * ages 50-64 * BMI 25-40 * Sedentary or low-active, defined as participating in \< 60 min/week of structured exercise * Has a smart phone that can connect to the internet at least once every few days and is compatible with smartphone app Exclusion criteria: * Medical symptoms/conditions that may make unsupervised exercise unsafe (specific exclusion criteria were developed in consultation with a cardiologist and are listed below): * Past 3-month overnight hospitalization * Past 3-month treatment for heart disease, including bypass or valve surgery, interventional procedure(s) such as angioplasty (stent), or a pacemaker or other implanted device to control your heart rate or rhythm * Past 3-month inability to walk without assistance due to stroke, transient ischemic attack (TIA), or neurologic or spinal injury * Past 6-month angina, chest pain, or chest discomfort either at rest or with exertion/activity * Past 6-month peripheral vascular disease such as claudication which causes pain in the legs when walking briskly * Past 6-month seizure * Past 6-month overnight hospitalization due to respiratory disease * Past 6-month lightheadedness, vertigo, dizziness, or fainting * Heart, lung, abdominal, joint, or orthopedic surgeries in the past 12-months, or pending or scheduled in the next 12 months * Takes insulin and/or medication that affects the secretion of insulin * Exercise-induced asthma that prevents brisk walking * Takes anticonvulsant medication or medication to treat/control seizures * Diagnosed with cystic fibrosis * Bone or joint problems that make you unable to walk for at least 30 minutes * Physician has said not to exercise because of bone or joint problems * Physician has said a hip or knee replacement will be needed in the next 12 months * Anything other medical symptoms/condition that prevents participant from being physical unable to walk without assistance continuously for 30 minutes * Currently taking or planning on taking medications that affect HR, such as beta or calcium channel blockers or digoxin, as HR will be used to determine the moderate intensity range for participants assigned to that condition * Past 12-month overnight psychiatric hospitalization * Currently pregnant or planning to become pregnant in the next year * Currently participating in any exercise or weight-loss research studies * Household member is participating in this study * Does not have a Rhode Island mailing address OR if only Rhode Island mailing address is a PO box * Unable to receive materials in the mail at residential mailing address * Does not plan to live in Rhode Island for the next 12 months * Unable to speak, read, and/or write fluently in English * Smokers will be eligible, but smoking status will be included as a covariate in analyses

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Conditions

The condition(s) this trial relates to.

Motor Activity Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brown University

    Providence, Rhode Island, 02912, United States

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