New triple-drug attack targets hard-to-treat head and neck cancers

NCT ID NCT06912087

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 31 times

Summary

This early-phase study tests a new three-drug combination (zanzalintinib, pembrolizumab, and cetuximab) in adults with recurrent or metastatic head and neck cancer that cannot be cured by local treatments. The main goal is to find the safest dose and check for early signs of tumor shrinkage. About 36 participants will take part at the University of Chicago.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Chicago Medicine Comprehensive Cancer Center

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.