HEAD AND NECK NEOPLASMS

This study tested a new oral drug, afatinib, against a standard intravenous chemotherapy, methotrexate, in 340 adults with advanced head and neck cancer that had worsened after platinum-based treatment. The main goal was to see if afatinib could delay cancer growth better than me…

This study tested a combination of two drugs, atezolizumab and bevacizumab, in 33 adults with advanced head and neck cancer that had already been treated with chemotherapy. The goal was to see if the combination could shrink tumors or stop the cancer from growing. The study was c…

This study tested a combination of two drugs, pembrolizumab and cetuximab, in 78 people with advanced head and neck cancer that had come back or spread. Participants were grouped based on whether they had tried these drugs before. The goal was to see if the combination could shri…

This study looked at people with advanced head and neck cancer that had spread to lymph nodes. It compared two approaches: having surgery to remove those lymph nodes before chemo-radiation, versus chemo-radiation alone. The goal was to see if the surgery could reduce side effects…

This study tested whether adding the immunotherapy drug pembrolizumab to standard chemoradiation could help people with advanced head and neck cancer live longer without their disease getting worse. About 800 participants were randomly assigned to receive either pembrolizumab plu…

This study tested whether adding manual acupuncture to standard chemoradiation helps head and neck cancer patients. 34 adults received either real or sham acupuncture three times a week. Researchers measured fatigue, quality of life, and white blood cell counts to see if acupunct…

This study tested two treatments—laser therapy and ozone gas—for painful mouth sores caused by cancer treatment. Forty adults with head/neck or blood cancers took part. Each group received daily therapy for five days, and researchers tracked soreness, pain, and quality of life fo…

This study looked at whether active nutritional support can lower the chance of painful mouth sores (mucositis) and improve quality of life in adults with head and neck cancer who are getting radiation therapy. 47 newly diagnosed patients were followed to track their weight and b…

This study tested a new way to give radiation therapy to people with head and neck cancer. The goal was to see if lowering the radiation dose to the neck (while still treating the main tumor) could reduce long-term side effects like trouble eating and improve quality of life. Abo…

This study tested whether a short exercise program before chemoradiotherapy helps head and neck cancer patients maintain physical function. 47 adults with head and neck cancer were randomly assigned to either an exercise prehabilitation group or usual care. The exercise group did…

This study looked back at whether ozone therapy could help treat painful mouth sores in patients receiving radiation or chemotherapy for head and neck cancer. It involved 38 patients who received professional ozone treatments and used special ozonated oils at home. Researchers me…

This completed study tested a new way to create 3D models of nerves in the head and neck area using MRI scans from 7 children aged 1 to 5. The goal was to help surgeons better plan operations for tumors or birth defects by seeing exactly where important nerves are located. The re…

This study looked at whether a special PET scan called FMISO can measure oxygen levels in head and neck tumors. Sixteen adults with head and neck cancer received the scan before starting radiation therapy. Researchers then checked if the scan results matched how well the cancer r…