New drug cocktail shows promise for tough head and neck cancers

NCT ID NCT03818061

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a combination of two drugs, atezolizumab and bevacizumab, in 33 adults with advanced head and neck cancer that had worsened after chemotherapy. The goal was to see if the combo could shrink tumors or slow disease progression. Results may help guide future treatments for this hard-to-treat cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Atezolizumab (Tecentriq) and Bevacizumab (Avastin)

What this could lead to

If it works, this could point toward a new treatment option for people with advanced head and neck cancer that has stopped responding to chemotherapy.

What could go wrong

This is a small, early-phase study with only 33 participants, so results may not apply to everyone. The combination may cause side effects like high blood pressure or immune-related reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck neoplasm Head and Neck Neoplasms head and neck squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Antoine Lacassagne

    Nice, 06189, France

  • Centre Henri Becquerel

    Rouen, 76038, France

  • Centre Léon Bérard

    Lyon, 69373, France

  • Centre Paul Strauss

    Strasbourg, 67065, France

  • Clinique Mutualiste de l'Estuaire

    Saint-Nazaire, 44606, France

  • Institut Claudius Regaud

    Toulouse, 31059, France

  • Institut Curie

    Paris, 75005, France