Drug combo shows promise for tough head and neck cancers

NCT ID NCT03691714

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 study tested two drugs—durvalumab and cetuximab—together in 35 people with head and neck cancer that had come back or spread and was no longer responding to standard treatments. The goal was to see if the combination could shrink tumors. The study is complete, and results help guide future research.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
durvalumab and cetuximab
What this could lead to
If successful, this combination could offer a new treatment option for people with head and neck cancer that has returned or spread.
What could go wrong
This is a small, early-phase study (35 people) with no control group. The combination may cause serious side effects, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UC Health

    Cincinnati, Ohio, 45219, United States

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Other studies related to the condition(s) this trial covers.