Drug combo shows promise for tough head and neck cancers

NCT ID NCT03691714

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 study tested two drugs—durvalumab and cetuximab—together in 35 people with head and neck cancer that had come back or spread and was no longer responding to standard treatments. The goal was to see if the combination could shrink tumors. The study is complete, and results help guide future research.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

durvalumab and cetuximab

What this could lead to

If successful, this combination could offer a new treatment option for people with head and neck cancer that has returned or spread.

What could go wrong

This is a small, early-phase study (35 people) with no control group. The combination may cause serious side effects, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck cancer head and neck neoplasm Head and Neck Neoplasms head and neck squamous cell carcinoma metastatic malignant neoplasm Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UC Health

    Cincinnati, Ohio, 45219, United States