Tissue analysis may guide personalized cancer therapy
NCT ID NCT01856296
First seen Aug 10, 2026 · Last updated Aug 12, 2026 · Updated 2 times
Summary
This study tests whether analyzing a patient's tumor alongside a sample of their normal tissue can help doctors select a more effective treatment for advanced cancer. The approach aims to provide a personalized therapy choice for every participant, even those without known genetic mutations. Researchers will compare how long the chosen treatment controls the cancer versus the previous treatment. The study involves adults with metastatic cancer who can safely undergo a biopsy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Biopsy procedure for molecular analysis
- What this could lead to
- If successful, this approach could help doctors choose more effective, personalized treatments for people with advanced cancer, potentially improving survival.
- What could go wrong
- This is an early-stage exploratory study, and the benefit of this biopsy-guided approach is not yet proven. It may not work for all patients or cancer types, and biopsies carry risks like bleeding or infection.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Institut Gustave Roussy
Villejuif, Val de Marne, 94805, France
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