Can a new drug combo shrink Hard-to-Treat salivary gland tumors?
NCT ID NCT05010629
First seen Aug 07, 2026 · Last updated Aug 07, 2026
Summary
This phase 2 trial is testing whether an experimental drug called 9-ING-41, when combined with the chemotherapy drug carboplatin, can help people with advanced or metastatic salivary gland cancer. The study aims to see if the combination can shrink tumors or slow their growth. Participants receive both drugs through an IV, and the trial will measure how many people respond to treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 9-ING-41 (a GSK-3β inhibitor) combined with carboplatin chemotherapy
- What this could lead to
- If effective, this combination could offer a new treatment option to slow or shrink advanced salivary gland tumors, potentially improving outcomes for patients with limited choices.
- What could go wrong
- This is a phase 2 trial with a small number of participants, so results may not be conclusive. The drug combination may cause side effects, and it is not yet known if it will work better than standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
-
Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Other studies related to the condition(s) this trial covers.
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