Ozone treatment eases painful mouth sores in cancer patients
NCT ID NCT07247799
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether ozone therapy can help treat oral mucositis—painful mouth sores—in 38 patients receiving radiation and chemotherapy for head and neck cancer. Patients received in-office ozone gas treatment plus at-home ozonated oil products. The researchers measured changes in sore severity, pain levels, and quality of life. The goal was to see if this approach could reduce discomfort and improve daily activities like eating.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ozone therapy (medical ozone gas and ozonated oil products)
- What this could lead to
- If effective, ozone therapy could offer a simple, non-drug way to reduce painful mouth sores and improve eating and quality of life during cancer treatment.
- What could go wrong
- This is a small, retrospective study with only 38 participants and no comparison group. Results may not apply to all patients, and ozone therapy is not yet a standard treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEAD AND NECK NEOPLASMS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Unit of Dental Hygiene - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Paediatrics - University of Pavia
Pavia, Lombardy, 27100, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- One drop, many cancers? a rapid test aims to spot cancer signals in blood, urine, or saliva
- Olive oil and xylitol mouth rinse may shield cancer patients from painful mouth sores
- Can laser or ozone therapy better soothe cancer-related mouth pain? a head-to-head comparison
- Touch and tingle: Non-Drug therapies aim to tame chemo side effects
- Plant pigment could soothe Radiation's harsh side effect in blood cancer treatment
- Could a laser beam stop chemo mouth sores?