Ozone treatment eases painful mouth sores in cancer patients
NCT ID NCT07247799
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether ozone therapy can help treat oral mucositis—painful mouth sores—in 38 patients receiving radiation and chemotherapy for head and neck cancer. Patients received in-office ozone gas treatment plus at-home ozonated oil products. The researchers measured changes in sore severity, pain levels, and quality of life. The goal was to see if this approach could reduce discomfort and improve daily activities like eating.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ozone therapy (medical ozone gas and ozonated oil products)
What this could lead to
If effective, ozone therapy could offer a simple, non-drug way to reduce painful mouth sores and improve eating and quality of life during cancer treatment.
What could go wrong
This is a small, retrospective study with only 38 participants and no comparison group. Results may not apply to all patients, and ozone therapy is not yet a standard treatment.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Unit of Dental Hygiene - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Paediatrics - University of Pavia
Pavia, Lombardy, 27100, Italy