Which drug stops preterm labor best? new study pits nifedipine against magnesium sulfate

NCT ID NCT05343806

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two drugs—nifedipine (a pill) and magnesium sulfate (given through a vein)—to see which is better at delaying preterm labor in pregnant women between 32 and 36 weeks. A total of 264 women took part, and the main goal was to see how many avoided giving birth within 48 hours of starting treatment. The hope is that delaying labor gives time for steroids to help the baby's lungs develop, reducing health risks for newborns.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nifedipine and magnesium sulfate

What this could lead to

If one drug works better, it could help more women delay preterm labor long enough for steroids to mature the baby's lungs, reducing newborn complications.

What could go wrong

This is a single-center trial with 264 participants, so results may not apply to all pregnant women. Both drugs have side effects like low blood pressure or breathing issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Medicine, Assiut University

    Asyut, Asyut Governorate, 71515, Egypt