Can dexmedetomidine or lidocaine replace opioids for gallbladder surgery pain?
NCT ID NCT05788393
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed trial tested whether giving dexmedetomidine or lidocaine continuously during gallbladder surgery can control pain afterward and reduce the need for opioids. 64 adults undergoing laparoscopic cholecystectomy were randomly assigned to receive one of the two drugs. The main goal was to measure pain scores using a 0-10 scale after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dexmedetomidine and lidocaine
What this could lead to
If successful, this could show that either drug effectively controls pain after gallbladder surgery while reducing the need for opioids.
What could go wrong
This is a small, completed Phase 4 trial with only 64 participants, so results may not apply to everyone. The study compares two drugs but does not test a new treatment.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Assiut university hospitals
Asyut, Asyut Governorate, Egypt