Can dexmedetomidine or lidocaine replace opioids for gallbladder surgery pain?

NCT ID NCT05788393

Completed Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed trial tested whether giving dexmedetomidine or lidocaine continuously during gallbladder surgery can control pain afterward and reduce the need for opioids. 64 adults undergoing laparoscopic cholecystectomy were randomly assigned to receive one of the two drugs. The main goal was to measure pain scores using a 0-10 scale after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dexmedetomidine and lidocaine
What this could lead to: If successful, this could show that either drug effectively controls pain after gallbladder surgery while reducing the need for opioids.
What could go wrong: This is a small, completed Phase 4 trial with only 64 participants, so results may not apply to everyone. The study compares two drugs but does not test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

agnosia pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANALGESIA

Contacts and locations

Locations

Assiut university hospitals

Asyut, Asyut Governorate, Egypt

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