Assiut University

This study tests whether a new surgical guide (the Alfonso nomogram) helps doctors place corneal ring implants more effectively in people with moderate keratoconus. Twenty-five adults aged 18–35 with progressive disease received the implant. Researchers will measure changes in vi…

This study looks at 150 adults with COPD who have just had a breathing tube removed. It compares two ways to help them breathe: a high-flow nasal cannula (a soft tube that delivers warm, moist oxygen) versus noninvasive ventilation (a mask that pushes air into the lungs). The goa…

This trial compares two non-invasive breathing support methods—high-flow nasal cannula (HFNC) and non-invasive ventilation (NIV)—in 100 adults with acute pulmonary embolism and respiratory failure. The goal is to see which method helps patients breathe on their own within 48 hour…

This study looks at a new, less invasive way to remove plaque from leg arteries in people with severe blockages that threaten the limb. About 60 participants will get the procedure, called atherectomy, to see if it can restore blood flow without needing more surgery. The goal is …

This study tests whether the drug dexmedetomidine, given during liver transplant surgery, can protect the new liver and other organs from injury. Sixty adults receiving a living-donor liver transplant will be randomly assigned to receive either the drug or a placebo. The goal is …

This study compares a new, minimally invasive keyhole surgery (endoscopic parotidectomy) to the standard open surgery for removing benign (non-cancerous) tumors from the parotid gland, a major salivary gland. The goal is to see if the keyhole approach is as safe and effective, wi…

This study compares two surgical techniques for treating various Achilles tendon disorders, such as chronic tears and tendinopathy. One method uses a small camera (endoscopic) and the other uses a larger open incision. The goal is to see which approach leads to better function, f…

This study looks at whether starting to walk earlier after a type of knee surgery (open wedge high tibial osteotomy) helps reduce pain and improve function in people with knee osteoarthritis. About 72 participants will either start partial weight bearing at 2 weeks or wait until …

This study compares a standard physical therapy program with a targeted exercise program designed to improve knee alignment in adults aged 30-55 with mild to moderate knee osteoarthritis and bow-legged alignment. About 80 participants will do either standard exercises or specific…

This study looks at whether adding a blood flow restriction cuff to targeted exercises helps adults aged 30-55 with mild to moderate knee osteoarthritis and bow legs feel less pain and move better. About 80 participants will be randomly assigned to do exercises either with or wit…

This study tests a surgical procedure called partial wrist denervation, done at the same time as standard fracture repair, to see if it reduces the chance of long-term wrist pain. Researchers are enrolling 56 adults with severe, shattered wrist fractures. The main goal is to meas…

This study compares two types of nerve blocks (PECS II-PIFB vs. SAPB) to see which provides better pain relief for women undergoing modified radical mastectomy. Seventy women aged 18-65 will be enrolled, and the main goal is to measure how much extra pain medicine they need in th…

This study compares two methods of removing the outer layer of the cornea during PRK laser eye surgery. One method uses a laser to remove the layer, while the other uses a manual tool. The goal is to see which approach leads to better vision and faster healing. About 100 people a…

This study follows 1,423 adults with idiopathic pulmonary fibrosis (IPF) for two years to learn how the disease progresses naturally. Researchers will track events like sudden worsening, hospital stays, and deaths. The goal is to better understand IPF patterns, not to test a new …

This study looks at knee injuries in children under 18 who were treated at Assiut University Hospitals between 2022 and 2025. Researchers will collect information on how common these injuries are and what types occur. The goal is to create a secure database that can help guide fu…

This study looks at sleep quality in 60 adults with non-cystic fibrosis bronchiectasis, a chronic lung condition. Researchers will measure how well participants sleep and see if poor sleep is linked to more severe lung disease, worse breathing tests, or more lung damage on CT sca…

This study follows 50 people who had a minimally invasive procedure to widen a narrowed heart valve (pulmonary balloon valvuloplasty). The goal is to see how often the right side of the heart struggles afterward and what factors might predict that. Researchers will track changes …