Can a sedative shield livers from transplant damage?
NCT ID NCT05031026
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether the drug dexmedetomidine, given during liver transplant surgery, can protect the new liver and other organs from injury. Sixty adults receiving a living-donor liver transplant will be randomly assigned to receive either the drug or a placebo. The goal is to see if the drug reduces damage to blood vessel linings and lowers the risk of early liver failure or other complications.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dexmedetomidine (also known as Precedex)
What this could lead to
If it works, this could point toward a way to protect the new liver and other organs from damage during transplant surgery.
What could go wrong
This is a small, early-phase study with only 60 participants, so results may not apply to everyone. The drug may not show a clear benefit over placebo.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Assiut University
Asyut, 088, Egypt