Which breathing aid wins for lung clots? new trial aims to find out

NCT ID NCT07381712

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial compares two non-invasive breathing support methods—high-flow nasal cannula (HFNC) and non-invasive ventilation (NIV)—in 100 adults with acute pulmonary embolism and respiratory failure. The goal is to see which method helps patients breathe on their own within 48 hours and improves survival. Participants must be stable enough to avoid immediate intubation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

High-Flow Nasal Cannula (HFNC) and Non-Invasive Ventilation (NIV) devices

What this could lead to

If successful, this could show which breathing support method works better for pulmonary embolism patients, potentially improving weaning success and survival.

What could go wrong

This is a small, early-stage trial with only 100 participants, so results may not apply to all patients. The study is not yet recruiting, and outcomes depend on individual patient factors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Assiut University Hospitals

    Asyut, أسيوط - Asyut Governorate, 71511, Egypt