Which breathing aid wins for lung clots? new trial aims to find out

NCT ID NCT07381712

Ongoing Disease control Sponsor: Assiut University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial compares two non-invasive breathing support methods—high-flow nasal cannula (HFNC) and non-invasive ventilation (NIV)—in 100 adults with acute pulmonary embolism and respiratory failure. The goal is to see which method helps patients breathe on their own within 48 hours and improves survival. Participants must be stable enough to avoid immediate intubation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: High-Flow Nasal Cannula (HFNC) and Non-Invasive Ventilation (NIV) devices
What this could lead to: If successful, this could show which breathing support method works better for pulmonary embolism patients, potentially improving weaning success and survival.
What could go wrong: This is a small, early-stage trial with only 100 participants, so results may not apply to all patients. The study is not yet recruiting, and outcomes depend on individual patient factors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULMONARY EMBOLISM

Contacts and locations

Locations

Assiut University Hospitals

Asyut, أسيوط - Asyut Governorate, 71511, Egypt

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