Bladder cancer study questions whether chemo skews MRI results

NCT ID NCT07202819

Recruiting now Knowledge-focused Sponsor: Assiut University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial is investigating whether chemotherapy given before bladder removal surgery affects how accurate MRI scans are at staging muscle-invasive bladder cancer. Researchers will compare MRI results with actual tumor findings after surgery in 76 participants who either received chemo first or went straight to surgery. The goal is to understand if chemo-induced tissue changes make MRI less reliable.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Neoadjuvant chemotherapy (cisplatin-based regimens such as MVAC or gemcitabine and cisplatin)
What this could lead to: If successful, this study could help doctors know whether MRI scans remain reliable for staging bladder cancer after chemotherapy, improving treatment planning.
What could go wrong: This is a small, early-stage study focused on diagnostic accuracy, not a treatment. Results may not apply to all patients or change clinical practice directly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

infiltrating bladder urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MUSCLE-INVASIVE BLADDER CANCER

Contacts and locations

Locations

Urology Department, Faculty of Medicine, Assiut University
NOT_YET_RECRUITING

Asyut, Asyut Governorate, 71515, Egypt
Urology Department, Faculty of Medicine, Assiut University
RECRUITING

Asyut, Asyut Governorate, 71515, Egypt

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