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New study aims to unmask hidden causes of childhood joint stiffness

NCT ID NCT07173010

Not yet recruiting Knowledge-focused Sponsor: Assiut University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study will look at 35 children with joint problems that are not caused by inflammation, such as stiffness or deformity. Researchers will use exams, lab tests, and imaging to find the true cause, which could be rare genetic conditions like mucopolysaccharidoses or osteogenesis imperfecta. The goal is to improve diagnosis and prevent children from being treated incorrectly for inflammatory arthritis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors better diagnose rare joint conditions in children and avoid giving them unnecessary treatments meant for inflammatory arthritis.

What could go wrong

This is a small, early observational study at a single hospital, so findings may not apply to all children. It aims to gather knowledge, not test a new treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

camptodactyly-arthropathy-coxa vara-pericarditis syndrome Farber lipogranulomatosis Hyaline Fibromatosis Syndrome infantile systemic hyalinosis mucopolysaccharidosis multicentric carpo-tarsal osteolysis with or without nephropathy osteogenesis imperfecta Osteolysis, Essential progressive pseudorheumatoid arthropathy of childhood

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FARBER DISEASE IDIOPATHIC MULTICENTRIC OSTEOLYSIS INFANTILE SYSTEMIC HYALINOSIS MUCOPOLYSACCHARIDOSES OSTEOGENESIS IMPERFECTA PROGRESSIVE PSEUDORHEUMATOID DYSPLASIA

Contacts and locations

Study contacts

  • Contact

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