Can a common heart drug improve how the heart relaxes?
NCT ID NCT07157527
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at whether the drug sacubitril/valsartan (Entresto) can improve the heart's ability to relax in people with heart failure and reduced pumping strength. Researchers will use ultrasound to measure changes after six months of treatment. The study involves 70 adults from two heart centers in Egypt.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sacubitril/valsartan (Entresto)
What this could lead to
If successful, this could show that sacubitril/valsartan improves heart relaxation in patients with heart failure and reduced pumping ability, potentially guiding better treatment.
What could go wrong
This is a small, early-stage observational study with only 70 participants. It may not prove long-term benefits, and results may not apply to all heart failure patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.