Can 3D heart scans outperform standard ultrasound in predicting risk?

NCT ID NCT07741305

Recruiting now Knowledge-focused Sponsor: Istituti Clinici Scientifici Maugeri SpA Source: ClinicalTrials.gov ↗

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This study compares two ultrasound techniques—2D and 3D speckle-tracking echocardiography—to see which measures heart muscle contraction more accurately in people with heart failure and reduced pumping function. Researchers will enroll 419 patients from seven cardiac rehabilitation hospitals in Italy, analyzing images with standardized equipment. The goal is to see how closely the two methods agree, what factors cause differences, and whether 3D imaging better predicts the risk of death than the standard 2D approach.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If 3D ultrasound proves more accurate, it could lead to better heart function assessment and more precise risk prediction for heart failure patients.
What could go wrong: This is an observational comparison, not a treatment trial. The 3D technique may not show clear advantages over the standard 2D method, and results may not change current clinical practice.

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Conditions

The condition(s) this trial relates to.

heart failure systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

Locations

ICS Maugeri - Istituto di Bari
RECRUITING

Bari, BA, 70124, Italy
ICS Maugeri - Istituto di Milano
RECRUITING

Milan, MI, 20138, Italy
ICS Maugeri - Istituto di Pavia
RECRUITING

Pavia, PV, 27100, Italy
ICS Maugeri - Istituto di Veruno
RECRUITING

Veruno, 28013, Italy
ICS Maugeri Torino
RECRUITING

Torino, TO, 10124, Italy

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