Can a Breathing-Synchronized pacemaker boost heart function after bypass?
NCT ID NCT06359938
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This trial tests a new type of pacemaker for people with heart failure who are having coronary bypass surgery. The pacemaker is designed to mimic a natural pattern called respiratory sinus arrhythmia, where the heart rate speeds up when breathing in and slows down when breathing out. The study aims to see if this pacing approach is safe and whether it improves how well the heart pumps blood compared to standard pacing. Participants will be monitored closely during their hospital recovery and receive a follow-up call one month after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- A modified temporary external pacemaker that adjusts heart rate with breathing (respiratory sinus arrhythmia pacing)
- What this could lead to
- If it works, this pacing approach could improve heart output and recovery after bypass surgery in heart failure patients, potentially leading to a new standard of care.
- What could go wrong
- This is a small early-stage trial focused on safety and short-term effects, so benefits are uncertain. The pacemaker is temporary and only used during hospital recovery, and it may not improve long-term outcomes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cardiff & Vale University Health Board
Cardiff, Cardiff, CF14 4XW, United Kingdom
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