HEART FAILURE WITH REDUCED EJECTION FRACTION
Clinical trials for HEART FAILURE WITH REDUCED EJECTION FRACTION explained in plain language.
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Wireless sensor could help doctors Fine-Tune heart failure treatment in real time
Disease control Recruiting nowThis study tests whether a small wireless sensor placed in the pulmonary artery can help doctors better manage medications for people with heart failure and a leaky mitral valve. The sensor constantly measures pressure inside the heart, giving doctors real-time data to adjust tre…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Columbia University • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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New heart failure drug aims to cut hospitalizations and deaths
Disease control Recruiting nowThis study tests an investigational drug called omecamtiv mecarbil in 1,800 adults with severe heart failure and a very weak heart pump. The goal is to see if it can lower the risk of heart failure worsening, hospitalization, need for a heart pump or transplant, or death. Partici…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE3 • Sponsor: Cytokinetics • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Can weight loss drugs boost heart function in obese heart failure patients?
Disease control Recruiting nowThis study compares weight loss using semaglutide (a drug) versus a calorie-restricted diet in 100 people with obesity and heart failure with reduced ejection fraction. The goal is to see which approach better improves peak oxygen uptake, a measure of exercise capacity, after 52 …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE2, PHASE3 • Sponsor: Jens D Hove, MD,PHD • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Diabetes drug could help weak hearts after bypass surgery
Disease control Recruiting nowThis study looks at whether the diabetes drug dapagliflozin can improve how well the right side of the heart works after off-pump coronary bypass surgery. Researchers will measure heart function in 72 patients with weak hearts before and after 6 months of taking the drug. The goa…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Pyatigorsk City Clinical Hospital Number 1 • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New heart pacing method tested against standard therapy in 850 patients
Disease control Recruiting nowThis study compares a newer pacing method (Left Bundle Branch Area Pacing) with the standard cardiac resynchronization therapy for people with heart failure. About 850 adults with moderate to severe heart failure will take part. The goal is to see if the newer method reduces deat…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Boston Scientific Corporation • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Butter and bacon for a stronger heart? new trial puts high-fat diet to the test.
Disease control Recruiting nowThis study tests whether a carefully controlled high-fat diet can improve heart function in people with a specific type of heart failure (non-ischemic dilated cardiomyopathy). Researchers believe that switching the heart's fuel source back to fats may help it pump more effectivel…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New heart pacing technique could help when standard therapy fails
Disease control Recruiting nowThis study tests a new pacing method called left bundle branch area pacing for people with heart failure whose heart pumps less blood than normal (ejection fraction 50% or lower). It is for patients who cannot get standard pacing or need a backup option. The goal is to see if thi…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Diet and exercise combo may boost muscle in heart failure patients
Disease control Recruiting nowThis study tests whether a high-protein DASH diet, resistance exercise, or both can help people with heart failure and reduced ejection fraction maintain or increase muscle mass. About 100 adults over age 30 with stable heart failure will take part. The goal is to see if these li…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Medical University of Silesia • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Major trial tests if zapping heart tissue beats pills for common rhythm disorder
Disease control Recruiting nowThis study looks at whether a procedure called catheter ablation (using heat or cold to fix faulty heart signals) is better than standard medications for people with both atrial fibrillation and heart failure. About 1,200 adults will be randomly assigned to receive either ablatio…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: University College, London • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Digital platform aims to Fine-Tune heart failure drugs after hospital stay
Disease control Recruiting nowThis study tests whether a digital remote-management platform can help doctors better adjust heart failure medications after patients leave the hospital. About 252 adults with heart failure and reduced pumping function will use the platform to report symptoms and vital signs, wit…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Beijing Anzhen Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Heart failure checklist aims to boost lifesaving drug use
Disease control Recruiting nowThis study tests whether giving heart failure patients a one-page checklist of recommended medications helps doctors prescribe them more often. The checklist lists guideline-approved drugs and doses for heart failure with reduced ejection fraction. Researchers will enroll 4000 pa…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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New heart failure drug enters early human testing
Disease control Recruiting nowThis early-stage trial is testing an experimental drug called HJB647 in 12 adults with stable chronic heart failure and reduced pumping ability. The study aims to check the drug's safety and how the body processes it at two different doses. Participants will receive both the drug…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Heart failure recovery: could patients finally take fewer pills?
Disease control Recruiting nowThis study looks at whether people whose heart failure has improved can safely cut back on some of their daily medications. Participants will either continue all four standard drugs or gradually reduce to just two under close monitoring. The goal is to see if heart function stays…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE4 • Sponsor: Ziekenhuis Oost-Limburg • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New pacing method may outperform standard therapy in heart failure patients
Disease control Recruiting nowThis study compares two types of heart pacing—conduction system pacing and standard biventricular resynchronization—in 320 adults with heart failure and wide QRS. The goal is to see which method better reduces the risk of death, heart transplant, or hospitalization for heart fail…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Hospital Clinic of Barcelona • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Could a diaphragm pacemaker help failing hearts?
Disease control Recruiting nowThis study tests a device that stimulates the diaphragm in time with the heartbeat to help people with heart failure. Researchers will see if it improves heart function, exercise ability, and quality of life. About 270 participants will receive the device plus standard care, or s…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: VisCardia Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Web-Based heart failure program aims to cut hospital returns
Disease control Recruiting nowThis study tests whether a one-year program led by heart failure nurses, using online training and a mobile app, can reduce repeat hospital stays and improve quality of life for people with heart failure. About 200 adults who were recently hospitalized for worsening heart failure…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Herzzentrum Bremen • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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New drug aims to reverse heart damage in failure patients
Disease control Recruiting nowThis study tests a potential new medicine called CDR132L in 200 people with heart failure and an enlarged heart. Participants receive either CDR132L or a placebo by IV every 4 weeks for 48 weeks. The goal is to see if the drug can improve heart structure and function.
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Novo Nordisk A/S • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Heart failure drug withdrawal trial aims to free patients from lifelong pills
Disease control Recruiting nowThis study tests whether heart failure patients who fully recover after treatment for a fast heart rhythm (like atrial fibrillation) can safely stop their heart failure medications. 348 participants will be randomly assigned to either gradually stop their drugs or continue them a…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE2, PHASE3 • Sponsor: Herlev and Gentofte Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New device combo aims to ease heart failure burden
Disease control Recruiting nowThis study tests if using two devices together can help people with advanced heart failure. Participants get a CardioMems sensor to monitor heart pressure and later a BaroStim device to regulate blood pressure. The goal is to improve symptoms, walking ability, and reduce hospital…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE2, PHASE3 • Sponsor: Northwell Health • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Tiny lung artery implant aims to unburden failing hearts
Disease control Recruiting nowThis early study tests a device called ContraBand™, which is implanted in the lung arteries to reduce pressure on the heart. The goal is to see if it's safe and can improve exercise ability and symptoms in people with left-sided heart failure. About 55 adults with moderate to sev…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Restore Medical Ltd • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Air purifiers may boost heart failure Patients' walking ability
Disease control Recruiting nowThis study tests whether using portable air filters at home can improve the health of people with heart failure. Researchers will measure how far participants can walk in six minutes, along with blood pressure and heart-related blood markers. The study involves 255 adults in Indi…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: NYU Langone Health • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Heart failure drug before hospital stay may improve outcomes, study suggests
Disease control Recruiting nowThis study looks at 140 heart failure patients to see if taking a medicine called ARNI before coming to the hospital leads to better short-term health. Researchers will compare those who were already on ARNI with those who were not, tracking heart and kidney events during the hos…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Future University in Egypt • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Simple cuff trick may shield heart failure patients from kidney damage
Disease control Recruiting nowThis study tests whether briefly inflating a blood pressure cuff on the arm before a heart procedure can protect the kidneys and heart in people with congestive heart failure. About 240 participants will be randomly assigned to receive either the real cuff inflations or a sham ve…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE2, PHASE3 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Digital Check-Ins may Fine-Tune heart failure meds
Disease control Recruiting nowThis study tests whether using telemedicine (video or phone check-ins) can help doctors better adjust heart failure medications after patients leave the hospital. About 140 adults with heart failure and reduced pumping ability will be split into two groups: one gets usual care, t…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Protein power: new study tests if supplements can stop muscle loss in heart failure
Disease control Recruiting nowThis study looks at whether adding protein supplements to the diet can prevent muscle wasting in people with heart failure. About 120 adults with heart failure and reduced pumping ability will be randomly assigned to receive no, low, or high doses of protein drinks. The main goal…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Tufts Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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New program aims to get frail veterans into cardiac rehab
Disease control Recruiting nowThis study tests a program called Transition to Cardiac Rehabilitation (T2CR) for Veterans with heart disease who also have other health problems or frailty. The program starts in the hospital and continues at home, helping patients build skills and motivation to do cardiac rehab…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New clinic aims to tackle obesity and heart disease together
Disease control Recruiting nowThis study tests whether a cardiometabolic clinic can help obese adults with heart disease lose weight and improve health. Sixty participants will receive care from the clinic and be followed for 12 months. Researchers will measure weight loss, body mass index, and fat distributi…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Could a common heart pill help those with artificial valves?
Disease control Recruiting nowThis study tests whether the drug sacubitril/valsartan (Entresto) can improve heart function in people who have a prosthetic (artificial) heart valve and heart failure with reduced pumping ability. About 220 adults will either get the drug plus standard care, or standard care alo…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Kafrelsheikh University • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New pacing technique could help heart failure patients live longer
Disease control Recruiting nowThis study tests a newer heart pacing method (His or left bundle branch pacing) against the standard method (biventricular pacing) in over 2,000 adults with heart failure and a weak heart pump. The goal is to see which approach better improves quality of life, reduces hospital st…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Registry screening aims to close gaps in heart failure care
Disease control Recruiting nowThis study uses the Swedish Heart Failure Registry to identify people with heart failure and reduced ejection fraction who may need medication adjustments, iron deficiency screening, device therapy, or physiotherapy. Researchers will compare outcomes for 500 patients who receive …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Region Stockholm • Aim: Disease control
Last updated Jun 26, 2026 13:35 UTC
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AI stethoscope aims to spot silent heart and lung disease
Diagnosis Recruiting nowThis study is testing whether a digital stethoscope, combined with artificial intelligence, can detect two serious conditions: high blood pressure in the lungs (pulmonary hypertension) and a weak heart pump (low ejection fraction). About 3,850 adults will have their heart sounds …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Eko Devices, Inc. • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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Could a ring replace the blood pressure cuff for heart patients?
Diagnosis Recruiting nowThis study tests a wearable ring that measures blood pressure, comparing it to the standard 24-hour monitor in 100 people with heart failure and reduced pumping ability. The goal is to see if the ring is accurate and easy to use. If successful, it could make blood pressure tracki…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Keimyung University Dongsan Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 13:02 UTC
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Could eccentric exercise be the key to stronger hearts?
Symptom relief Recruiting nowThis study looks at whether a special type of exercise called eccentric training (where muscles lengthen under tension) can help people with heart failure and reduced pumping ability. Researchers will compare eccentric bike and strength training to standard cardio and strength ex…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: University Hospital, Antwerp • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Nerve zap could unclog heart failure lungs
Symptom relief Recruiting nowThis study tests whether blocking signals from the splanchnic nerve can reduce congestion and improve exercise ability in people with heart failure. About 54 adults with heart failure and reduced pumping function will receive either a nerve-blocking procedure or a sham procedure.…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Could a simple salt boost heart failure Patients' exercise ability?
Symptom relief Recruiting nowThis study tests whether a daily capsule of potassium nitrate (KNO3) can improve leg muscle power and overall exercise capacity in people with heart failure. 75 adults with reduced heart function will take either KNO3 or a placebo for 6 weeks. Researchers will measure changes in …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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App-Based program aims to help heart failure patients take control
Symptom relief Recruiting nowThis study tests a digital support program for 240 adults with heart failure. The program, accessed via a secure online portal, aims to help patients feel more in control of their condition and improve their quality of life. Participants use the program for six months, and resear…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Linkoeping University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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App-Based rehab could help heart failure patients get active at home
Symptom relief Recruiting nowThis study tests a home-based cardiac rehabilitation program delivered through a custom mobile app for people with heart failure. Participants use the app for education, mindfulness, and physical activity guidance, plus periodic video calls with an exercise physiologist. The goal…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Simple breathing device could help heart failure patients exercise better
Symptom relief Recruiting nowThis study tests whether adding inspiratory muscle training (using a device called PowerBreathe) to standard cardiac rehabilitation can improve how well the heart and muscles work during exercise in people with heart failure. Researchers will measure blood flow and oxygen use in …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Gene test may personalize Beta-Blocker dosing for heart failure
Knowledge-focused Recruiting nowThis study looks at whether a person's genetic makeup can predict how well they respond to the heart failure drug metoprolol. Researchers will give the drug to 100 people with heart failure and track their heart function and drug levels. The goal is to see if a genetic score can …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jul 01, 2026 23:00 UTC
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Diabetes Drug's hidden power: could it boost heart and muscle energy?
Knowledge-focused Recruiting nowThis study looks at how a common diabetes drug (SGLT2 inhibitor) changes the way the heart and muscles use energy from ketones. Researchers want to see if these changes can improve exercise ability and daily function in 30 adults with type 2 diabetes and heart failure. Participan…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: EARLY_PHASE1 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Scientists probe mitochondria to unlock heart failure secrets
Knowledge-focused Recruiting nowThis study looks at tiny structures inside heart cells called mitochondria in people with heart failure and clogged arteries. Researchers will take small heart tissue samples during bypass surgery and compare them with blood tests. They want to see if damaged mitochondria are lin…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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New heart MRI techniques could revolutionize stress testing
Knowledge-focused Recruiting nowThis study is testing new heart MRI techniques to see how the heart adapts to stress, like exercise or fluid changes. Researchers will study 135 healthy volunteers and people with heart conditions. The goal is to improve understanding of heart function and develop better diagnost…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Yale launches massive heart failure registry to monitor Real-World care
Knowledge-focused Recruiting nowThis study creates a live registry of up to 40,000 heart failure patients across the Yale New Haven Health System. Researchers will track hospitalizations and use of recommended therapies like beta blockers and ACE inhibitors. The goal is to monitor and improve heart failure care…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Denver study aims to close gap in heart failure care for underserved patients
Knowledge-focused Recruiting nowThis study looks at whether pharmacist-led medication checkups and easy-to-understand education can help people with heart failure get the right medicines. It involves 40 patients in Denver who have limited access to care. The goal is to see if this approach is practical and impr…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Denver Health and Hospital Authority • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Heart failure patients may finally ditch thirsty fluid rules
Knowledge-focused Recruiting nowThis study tests whether heart failure patients can safely drink as much fluid as they want instead of restricting it. Researchers will compare lung congestion, blood markers, quality of life, and hospital readmissions in 326 participants over time. The goal is to see if liberal …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Region Stockholm • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Could an 'Exercise-in-a-Pill' replace workouts for heart failure?
Knowledge-focused Recruiting nowThis study from Stanford University is looking at what happens inside the body when people with heart failure exercise. Researchers will measure thousands of proteins in the blood before and after a single workout, and again after a 12-week cardiac rehab program. By comparing the…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Can a diabetes drug boost heart fuel? new study investigates
Knowledge-focused Recruiting nowThis study looks at how SGLT2 inhibitors, a type of diabetes medicine, change energy levels in the heart and muscles. Researchers will measure key energy molecules in 71 adults with type 2 diabetes and heart failure. The goal is to understand how these drugs work, not to test a n…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: EARLY_PHASE1 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Johns hopkins launches study to uncover hidden cause of right heart failure
Knowledge-focused Recruiting nowThis study aims to understand why the right side of the heart fails in people with heart failure and high blood pressure in the lungs. Researchers will look at heart tissue samples from 50 adults to find the best ways to diagnose and treat this condition. Participants must be bet…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Heart failure registry aims to uncover best treatments
Knowledge-focused Recruiting nowThis study is tracking 4,000 people in the UK who were recently diagnosed with heart failure and have a weak heart pump (ejection fraction below 50%). Researchers will follow them over time to see how their health changes, what treatments they receive, and how often they are hosp…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Mid and South Essex NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Heart failure mystery: 3000 patients help doctors tailor treatments
Knowledge-focused Recruiting nowThis study is observing 3000 adults with various types of heart failure to learn how the disease develops and progresses. Researchers will collect medical records, blood samples, and imaging data to identify distinct patient groups. The goal is to match the right treatments to th…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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New algorithm aims to match heart failure patients with the right valve repair
Knowledge-focused Recruiting nowThis study tests a hospital-wide treatment guide for people with heart failure and a leaky mitral valve (secondary mitral regurgitation). The goal is to see if the guide helps doctors identify which patients will benefit most from a minimally invasive valve repair procedure calle…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Inova Health Care Services • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC