HEART FAILURE WITH REDUCED EJECTION FRACTION
Clinical trials for HEART FAILURE WITH REDUCED EJECTION FRACTION explained in plain language.
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New drug aims to cut heart failure hospitalizations and deaths
Disease control Recruiting nowThis study tests an investigational drug called omecamtiv mecarbil in 1800 adults with severe heart failure and a very weak heart pump. The goal is to see if the drug can lower the risk of serious events like hospitalization, need for a heart pump or transplant, stroke, or death.…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE3 • Sponsor: Cytokinetics • Aim: Disease control
Last updated May 17, 2026 00:31 UTC
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Heart failure remission: could you ditch the pills?
Disease control Recruiting nowThis study looks at people whose heart failure got better after treating a fast heart rhythm. It tests whether slowly stopping heart failure medicines is as safe as staying on them. About 348 adults in Denmark will be followed for a year to see if their heart stays healthy. The g…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE2, PHASE3 • Sponsor: Herlev and Gentofte Hospital • Aim: Disease control
Last updated May 17, 2026 00:29 UTC
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Digital heart helper: swiss trial tests telemedicine for better heart failure care
Disease control Recruiting nowThis study tests whether using telemedicine (smartphone or tablet check-ins) can help doctors fine-tune heart failure medications better than standard care. About 140 adults hospitalized with heart failure will be followed for 3 months after discharge. The goal is to see if digit…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Digital tool aims to Fine-Tune heart failure drugs
Disease control Recruiting nowThis study tests whether a smartphone or web-based platform can help doctors adjust heart failure medications more effectively than usual care. About 252 adults with heart failure and reduced pumping function will be randomly assigned to use the digital tool or receive standard f…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Beijing Anzhen Hospital • Aim: Disease control
Last updated May 12, 2026 13:39 UTC
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New pacing technique could help heart failure patients live longer
Disease control Recruiting nowThis study tests a newer heart pacing method (His or left bundle branch pacing) against the standard method (biventricular pacing) in over 2,100 adults with heart failure and a weak heart pump. The goal is to see if the newer method improves quality of life, reduces hospital stay…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated May 11, 2026 20:51 UTC
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Can a smartphone app replace hospital rehab for heart failure?
Disease control Recruiting nowThis study tests a home-based cardiac rehabilitation program delivered through a custom mobile app for people with heart failure. About 100 participants will be randomly assigned to either the app-based program or usual care. The goal is to see if the app helps increase physical …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated May 11, 2026 20:37 UTC
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Could a breathing pacemaker help failing hearts?
Disease control Recruiting nowThis study is testing a device that stimulates the diaphragm (the main breathing muscle) to see if it can improve heart function and quality of life in people with heart failure. About 270 participants with mild-to-moderate heart failure will receive the device plus standard medi…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: VisCardia Inc. • Aim: Disease control
Last updated May 05, 2026 11:56 UTC
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Can a smartphone app help heart failure patients feel more in control?
Symptom relief Recruiting nowThis study tests a digital support program for people with heart failure. The goal is to see if the program helps patients feel more in control of their condition and improves their quality of life. About 240 adults with heart failure will use the program for six months. Research…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Linkoeping University • Aim: Symptom relief
Last updated May 17, 2026 00:41 UTC
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Breathing workout may help heart failure patients get more from rehab
Symptom relief Recruiting nowThis study looks at whether adding special breathing exercises (inspiratory muscle training) to standard cardiac rehabilitation can improve how well the heart and muscles work during exercise in people with heart failure. Researchers at Mayo Clinic will enroll 70 adults with hear…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 17, 2026 00:40 UTC
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New heart failure drug HJB647 enters early human testing
Symptom relief Recruiting nowThis early-stage study tests a new drug called HJB647 in 12 adults with chronic stable heart failure and reduced pumping ability. The main goal is to check the drug's safety and how the body processes it. Participants will receive two different doses and a placebo in a random ord…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE1 • Sponsor: Novartis Pharmaceuticals • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC
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No-Implant heart shunt could ease failure symptoms
Symptom relief Recruiting nowThis early study tests a device that creates a small opening between the upper chambers of the heart to relieve pressure and improve symptoms in people with heart failure. About 20 adults with moderate to severe heart failure will receive the procedure. The main goal is to check …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: InterShunt Technologies, Inc. • Aim: Symptom relief
Last updated May 13, 2026 16:00 UTC
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Gene test could personalize heart failure treatment
Knowledge-focused Recruiting nowThis study looks at whether a person's genetic makeup affects how well the heart drug metoprolol works for heart failure. Researchers will give the drug to 100 people with heart failure and track their heart function and drug levels. The goal is to learn if a genetic score can he…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated May 17, 2026 00:41 UTC
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Heart failure mystery: 3000 patients join study to personalize treatment
Knowledge-focused Recruiting nowThis study is observing 3000 adults with various types of heart failure to learn how the disease develops and progresses. Researchers will collect medical data, blood samples, and imaging to find better ways to match treatments to individual patients. The goal is to improve preci…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 00:28 UTC
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40,000 heart patients monitored in real time
Knowledge-focused Recruiting nowThis study is creating a live registry to track heart failure patients across the Yale New Haven Health System. Researchers will monitor hospitalizations and use of recommended treatments in up to 40,000 participants. The goal is to better understand and improve heart failure car…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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Can a diabetes drug boost heart fuel? new study investigates
Knowledge-focused Recruiting nowThis study looks at how a common diabetes medication (SGLT2 inhibitor) changes energy levels in the heart muscle. Researchers will measure key energy molecules in the heart before and after treatment. The goal is to understand if this drug helps the heart work better in people wi…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: EARLY_PHASE1 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Researchers probe hidden heart muscle weakness in common heart failure
Knowledge-focused Recruiting nowThis study looks at why the right side of the heart fails in people with a common type of heart failure (reduced pumping ability). Researchers will check which medical tests best detect right heart muscle problems and test new treatments on heart tissue samples. About 50 adults w…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 06, 2026 16:01 UTC