Electronic nudge aims to close the gap in heart failure treatment
NCT ID NCT05433220
First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time
Summary
This study tests whether an electronic alert in a patient's medical record can prompt doctors to prescribe guideline-recommended heart failure medications that are not yet being used. The trial includes 5,000 adults with heart failure and a reduced ejection fraction (≤40%) seen at Inova clinics or hospitals. Half of the doctors will receive the alert when they open a patient's chart; the other half will continue with usual care. The goal is to see if the alert increases the number of patients on appropriate medications within 30 days.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Best practice advisory alert via electronic health record
- What this could lead to
- If effective, this alert system could help more heart failure patients receive life-saving medications, potentially reducing hospitalizations and deaths.
- What could go wrong
- The alert may not change prescribing habits, or doctors might ignore it. The study only measures short-term outcomes (30 days), so long-term benefits are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 5,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2022
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age\>18 Years * Seen by a Cardiologist in an Inova clinic or Inova hospital setting * Left Ventricular Ejection Fraction ≤40% Exclusion Criteria: * Opted out of EHR-based research * Hospice care * Already receiving maximally titrated doses of each of the four classes of evidence- based HFrEF medical therapy * Prior heart transplant
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Inova Health System
RECRUITINGFalls Church, Virginia, 22042, United States
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