Nerve zap could unclog heart failure lungs
NCT ID NCT06733012
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether blocking signals from the splanchnic nerve can reduce congestion and improve exercise ability in people with heart failure. About 54 adults with heart failure and reduced pumping function will receive either a nerve-blocking procedure or a sham procedure. The goal is to see if this approach safely eases symptoms and improves daily function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
catheter-based ablation of the right greater splanchnic nerve
What this could lead to
If it works, this could offer a new way to reduce heart failure symptoms like shortness of breath and fatigue, improving daily life.
What could go wrong
This is an early, small study (54 people) testing safety and effectiveness. The procedure carries risks like bleeding, infection, or nerve damage, and may not work for everyone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Duke
RECRUITINGDurham, North Carolina, 27278, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••