Scientists probe mitochondria to unlock heart failure secrets

NCT ID NCT05770349

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at tiny structures inside heart cells called mitochondria in people with heart failure and clogged arteries. Researchers will take small heart tissue samples during bypass surgery and compare them with blood tests. They want to see if damaged mitochondria are linked to worse outcomes like hospital stays or heart-related death. The goal is to better understand heart failure, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors better predict heart failure progression and tailor treatments based on mitochondrial health.

What could go wrong

This is a small, early observational study, so findings may not apply to all heart failure patients. It aims to understand, not treat, the condition.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder heart failure systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tomsk National Research Medical Center, Russian Academy of Sciences

    RECRUITING

    Tomsk, 634050, Russia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••