Scientists probe mitochondria to unlock heart failure secrets

NCT ID NCT05770349

Recruiting now Knowledge-focused Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at tiny structures inside heart cells called mitochondria in people with heart failure and clogged arteries. Researchers will take small heart tissue samples during bypass surgery and compare them with blood tests. They want to see if damaged mitochondria are linked to worse outcomes like hospital stays or heart-related death. The goal is to better understand heart failure, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors better predict heart failure progression and tailor treatments based on mitochondrial health.
What could go wrong: This is a small, early observational study, so findings may not apply to all heart failure patients. It aims to understand, not treat, the condition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder heart failure systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE HEART FAILURE

Contacts and locations

Locations

Tomsk National Research Medical Center, Russian Academy of Sciences
RECRUITING

Tomsk, 634050, Russia

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