Tiny lung artery implant aims to unburden failing hearts

NCT ID NCT05230745

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests a device called ContraBand™, which is implanted in the lung arteries to reduce pressure on the heart. The goal is to see if it's safe and can improve exercise ability and symptoms in people with left-sided heart failure. About 55 adults with moderate to severe heart failure will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ContraBand implant (a device placed in the pulmonary arteries to reduce pressure on the heart)

What this could lead to

If it works, this device could offer a new way to manage heart failure symptoms and improve daily function without open surgery.

What could go wrong

This is a small, early feasibility study with no control group, so results may not apply broadly. Risks include device-related complications like stroke, heart attack, or need for emergency surgery.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

heart failure left ventricular failure systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Site

    RECRUITING

    Aalst, Belgium

  • Clinical Site

    RECRUITING

    Antwerp, Belgium

  • Clinical Site

    RECRUITING

    Genk, Belgium

  • Clinical Site

    RECRUITING

    Lübeck, Germany

  • Clinical Site

    RECRUITING

    Nahariya, Israel

  • Clinical Site

    RECRUITING

    Petah Tikva, Israel

  • Clinical Site

    RECRUITING

    Klaipėda, Lithuania

  • Clinical Site

    RECRUITING

    Krakow, Poland

  • Clinical Site

    RECRUITING

    Lublin, Poland

  • Kaplan Medical Center

    RECRUITING

    Rehovot, Israel

  • Tbilisi Heart and Vascular Clinic

    RECRUITING

    Tbilisi, Georgia

  • Vilnius University Hospital Santaros Klinikos

    RECRUITING

    Vilnius, Lithuania