Gene test may personalize Beta-Blocker dosing for heart failure
NCT ID NCT07490067
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This study looks at whether a person's genetic makeup can predict how well they respond to the heart failure drug metoprolol. Researchers will give the drug to 100 people with heart failure and track their heart function and drug levels. The goal is to see if a genetic score can help doctors tailor beta-blocker doses for better results.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Metoprolol succinate (a beta-blocker drug)
What this could lead to
If successful, this could help doctors use a person's genetic score to choose the best beta-blocker dose for heart failure, making treatment more effective.
What could go wrong
This is a small, early-phase study (100 people) focused on understanding genetics, not proving a new treatment works. The genetic score may not reliably predict responses in real-world settings.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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