Simple cuff trick may shield heart failure patients from kidney damage
NCT ID NCT04982419
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether briefly inflating a blood pressure cuff on the arm before a heart procedure can protect the kidneys and heart in people with congestive heart failure. About 240 participants will be randomly assigned to receive either the real cuff inflations or a sham version. The goal is to see if this simple technique reduces kidney injury and improves walking ability after one month.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Remote ischemic preconditioning (blood pressure cuff inflations)
What this could lead to
If it works, this simple, non-drug technique could reduce kidney injury and improve recovery in heart failure patients after heart procedures.
What could go wrong
This is a mid-stage trial with 240 participants, so results are not yet proven. The benefit may be small or not apply to all patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hunter Holmes McGuire VA Medical Center, Richmond, VA
RECRUITINGRichmond, Virginia, 23249-0001, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX
RECRUITINGDallas, Texas, 75216-7167, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA
RECRUITINGPittsburgh, Pennsylvania, 15240, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••