New heart pacing method tested against standard therapy in 850 patients
NCT ID NCT07069738
First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 3 times
Summary
This study compares a newer pacing method (Left Bundle Branch Area Pacing) with the standard cardiac resynchronization therapy for people with heart failure. About 850 adults with moderate to severe heart failure will take part. The goal is to see if the newer method reduces death, need for heart transplant, or heart-related complications.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AdventHealth Tampa
RECRUITINGTampa, Florida, 33613, United States
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Alta Bates Summit Medical Center
RECRUITINGOakland, California, 94609, United States
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Arrhythmia Research Group
RECRUITINGJonesboro, Arkansas, 72401, United States
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Avera Heart Hospital of South Dakota
RECRUITINGSioux Falls, South Dakota, 57108, United States
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Baptist Hospital East Louisville
RECRUITINGLouisville, Kentucky, 40207, United States
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Capital Cardiology Associates
RECRUITINGAlbany, New York, 12211, United States
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Cardiology Associates Medical Group, Inc.
RECRUITINGVentura, California, 93003, United States
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Cedars Sinai Medical Center
RECRUITINGLos Angeles, California, 90048, United States
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Centracare Heart and Vascular Center
RECRUITINGSaint Cloud, Minnesota, 56303, United States
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Christus Trinity Mother Frances Health System
RECRUITINGTyler, Texas, 75701, United States
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Community Heart and Vascular Hospital
RECRUITINGIndianapolis, Indiana, 46250, United States
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Corewell Health
RECRUITINGGrand Rapids, Michigan, 49525, United States
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Duke University Medical Center
RECRUITINGDurham, North Carolina, 27710, United States
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Emory University Hospital
RECRUITINGAtlanta, Georgia, 30322, United States
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Heart Center Research, LLC
RECRUITINGHuntsville, Alabama, 35801, United States
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Heart Hospital Baylor Plano
RECRUITINGPlano, Texas, 75093, United States
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Mayo Clinic Phoenix
RECRUITINGPhoenix, Arizona, 85054, United States
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Midwest Cardiovascular Institute
RECRUITINGNaperville, Illinois, 60540, United States
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Mobile Infirmary Medical Center
RECRUITINGMobile, Alabama, 36608, United States
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Morristown Medical Center
RECRUITINGMorristown, New Jersey, 07932, United States
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Mount Carmel Health System
RECRUITINGColumbus, Ohio, 43219, United States
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New York Hospital Queens
RECRUITINGFlushing, New York, 11355, United States
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OhioHealth Research and Innovation Institute-Riverside Methodist Hospital
RECRUITINGColumbus, Ohio, 43214, United States
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Pacific Heart Institute
RECRUITINGSanta Monica, California, 90404, United States
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Penn Presbyterian Medical Center
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Rochester General Hospital
RECRUITINGNew York, New York, 14621, United States
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SUNY-Upstate Medical University
RECRUITINGSyracuse, New York, 13057, United States
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Sarasota Memorial Hospital
RECRUITINGSarasota, Florida, 34239, United States
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Scripps Memorial Hospital
RECRUITINGLa Jolla, California, 92037, United States
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Southcoast Physicians Group
RECRUITINGFall River, Massachusetts, 02720, United States
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St. Mary's Duluth Clinic Regional Heart Center
RECRUITINGDuluth, Minnesota, 55805, United States
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St.Thomas Health
RECRUITINGNashville, Tennessee, 37205, United States
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Torrance Medical Center
RECRUITINGTorrance, California, 90505, United States
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University of Chicago
RECRUITINGHinsdale, Illinois, 60521, United States
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University of Iowa Hospitals and Clinics
RECRUITINGIowa City, Iowa, 52242, United States
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University of Michigan Hospitals
RECRUITINGAnn Arbor, Michigan, 48109, United States
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Washington Hospital Center
RECRUITINGWashington D.C., District of Columbia, 20010, United States
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Weill Cornell Medical University
RECRUITINGNew York, New York, 10021, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could continuing a common heart drug before surgery save lives?
- Could a natural chemical be the key to safer heart failure treatment?
- Can a Breathing-Synchronized pacemaker boost heart function after bypass?
- Can 3D heart scans outperform standard ultrasound in predicting risk?
- Iron infusions put to the test for heart failure stamina
- Zapping lung nerves could ease heart Failure-Related high blood pressure