Boston Scientific Corporation

This study is tracking 1000 people with atrial fibrillation who receive the WATCHMAN FLX Pro device, a small implant that closes off a part of the heart to prevent blood clots from causing strokes. The goal is to see how safe and effective the device is in everyday medical practi…

This study tracks 200 adults with obesity in the EU who choose to get the Orbera365 intragastric balloon. The balloon is placed in the stomach and filled with saline to help people feel full and eat less. Researchers will monitor serious side effects and how much weight participa…

This study is testing a pacemaker lead placed in a specific area of the heart called the left bundle branch area. The goal is to see if this placement is safe and helps the heart beat more naturally in people with slow heart rates. About 140 participants will get the lead and be …

This study follows 4800 adults who use a Boston Scientific neurostimulation device for pain. It aims to see how well the device works in everyday life, including pain relief and quality of life. Participants are already scheduled to try the device as part of their normal care.

This registry is collecting information from 1,500 people with Parkinson's disease who are receiving deep brain stimulation (DBS) with the Vercise system. The goal is to see how DBS affects quality of life in everyday practice, and to evaluate new programming tools. Participants …

This study is tracking how well the VERCISE™ deep brain stimulation (DBS) system works for people with dystonia, a movement disorder causing muscle spasms. Researchers will follow 300 participants aged 7 and older who are already receiving DBS to see if their symptoms improve. Th…

This study tests a new device called FARAFLEX that uses electrical pulses to treat atrial fibrillation (AF), a condition where the heart beats irregularly. About 571 adults with AF that hasn't improved with medication will get this procedure. The goal is to see if it safely resto…

This study is testing whether it is safe and effective to perform two heart procedures at the same time in people with atrial fibrillation (AF). The first procedure uses pulsed field ablation to correct the heart's rhythm, and the second closes off a small pouch in the heart to r…

This study compares a newer pacing method (Left Bundle Branch Area Pacing) with the standard cardiac resynchronization therapy for people with heart failure. About 850 adults with moderate to severe heart failure will take part. The goal is to see if the newer method reduces deat…

This study is collecting information from 500 people with essential tremor who are using a Boston Scientific deep brain stimulation (DBS) system, which is already approved for use. The goal is to see how the device affects quality of life in real-world settings, not just in contr…

This study tests whether adding extra scar lines in the heart, along with the standard vein isolation procedure, helps people with persistent atrial fibrillation stay in normal rhythm longer. About 640 adults aged 18–80 with symptomatic, drug-resistant persistent AFib will be ran…

This early study tests a device called TheraSphere GBM in 36 people whose glioblastoma has come back after prior treatment. The device delivers tiny radioactive beads directly to the tumor to try to control it. The main goal is to check if the procedure is safe, not yet whether i…

This study tests whether a drug-coated balloon can be a safe and effective alternative to stents for treating new blockages in heart arteries. About 1,616 people will be randomly assigned to receive either the balloon or standard stent treatment. The goal is to see if the balloon…

This study tracks 500 Chinese patients with paroxysmal atrial fibrillation who are treated with the FARAPULSE pulsed field ablation system as part of their normal care. Researchers will monitor safety and effectiveness for up to three years. The goal is to see how well the device…

This study tests a temporary stomach balloon called Orbera365 to help people with obesity lose weight. About 144 adults with a BMI between 28 and 50 who have not succeeded with diet and exercise will get the balloon. The main goal is to see if at least 5% of body weight is lost a…

This study is testing the FARAPULSE Pulsed Field Ablation system in 376 people with persistent atrial fibrillation (AFib) who have already had a prior ablation. The device uses electrical pulses to destroy the heart tissue causing the abnormal rhythm. The goal is to see if it is …

This study is testing a new device called the FARAFLEX system, which uses targeted electrical pulses to treat atrial fibrillation, a common heart rhythm problem. About 250 adults with persistent or paroxysmal atrial fibrillation will take part. The goal is to see if the device is…

This study tests new waveforms delivered by the FARAPULSE PFA system to treat atrial fibrillation, a common heart rhythm problem. About 200 adults with paroxysmal or persistent atrial fibrillation will receive the procedure. The goal is to see if these new waveforms are safe and …

This study tests a sponge device called Endo-SPONGE to treat leaks that can happen after colorectal surgery. The sponge is placed into the leak cavity and uses suction to drain fluid and help the leak close. Researchers will check if the sponge is safe and effective in 66 adults,…

This study tests doing two heart procedures at the same time for people with atrial fibrillation. First, doctors use pulsed field energy to fix the heart's rhythm. Then, they implant a small device to close off a part of the heart where clots can form. The goal is to see if this …

This study is testing a treatment called BSJ019T in Japanese patients with liver cancer that cannot be removed by surgery and has not responded to standard treatments. The goal is to see if the treatment can control the cancer's growth and how safe it is. About 51 participants wi…

This study will test a device called EkoSonic in 30 Chinese patients with acute pulmonary embolism (blood clots in the lungs). The device uses ultrasound to help break up clots while delivering clot-busting medicine. The main goal is to see if it improves heart function within 48…

This study is collecting information from 5,000 people with peripheral vascular disease who are being treated with Boston Scientific drug-eluting devices in everyday medical practice. The goal is to see how well these devices work and how safe they are in a wide range of patients…

This study tests a procedure called transoral outlet reduction (TORe) combined with intensive lifestyle changes for people who have regained weight after gastric bypass surgery. About 108 participants will be randomly assigned to either receive the TORe procedure plus lifestyle c…

This study is testing a new way to use an already-approved spinal cord stimulator to treat chronic, hard-to-manage back and leg pain. The device sends mild electrical pulses to the spine, and the new setting (called TVP-SCS) varies the timing of those pulses. Researchers will enr…

This study is following 1,500 people with chronic low back pain caused by a condition called vertebrogenic pain syndrome. All participants will receive the Intracept procedure, which uses radiofrequency energy to ablate (disable) certain nerves in the spine thought to cause pain.…

This study tests whether a wearable Holter monitor can detect early signs of fainting in people with orthostatic hypotension or reflex syncope. Forty adults who have already had a tilt-table test will wear the monitor for up to 21 days. The goal is to see if the device can pick u…

This study is testing a wearable mask that measures breathing by tracking carbon dioxide in exhaled air and lung capacity. About 50 healthy adult volunteers will wear the mask at rest and during exercise. The goal is to compare two ways of measuring breathing rate to see which wo…

This study will look at the medical records of 15,000 people with chronic pain to see how well different treatments, like spinal cord stimulation, worked for them. The goal is to learn which approaches provide the best pain relief. No new treatments are being tested; instead, res…

This study is collecting information from 200 people with Parkinson's disease, dystonia, essential tremor, or other movement disorders who are scheduled to receive radiofrequency (RF) ablation—a procedure that uses heat to target small areas in the brain. The goal is to see how p…

This study reviews the medical records of up to 5,000 people who have received deep brain stimulation (DBS) for Parkinson's disease, essential tremor, or dystonia. Researchers want to see how well DBS improves symptoms over time in real-world settings. No new treatments are given…

This study involves 100 adults with heart rhythm problems who are already scheduled for a standard heart mapping procedure. Researchers will test new software features on the mapping system to see how well they work. The goal is to gather feedback to improve future versions of th…

This registry is a large-scale effort to monitor the safety and performance of Boston Scientific cardiac devices, including pacemakers and ablation tools, in 12,500 patients. It collects data from routine procedures and follow-ups to see how well the devices work and if any compl…