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New pacemaker lead aims to keep Heart's natural rhythm

NCT ID NCT07209852

Recruiting now Disease control Sponsor: Boston Scientific Corporation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 7 times

Summary

This study is testing a pacemaker lead placed in a specific area of the heart called the left bundle branch area. The goal is to see if this placement is safe and helps the heart beat more naturally in people with slow heart rates. About 140 participants will get the lead and be followed over time. The study is observational, meaning researchers will watch what happens without comparing to another treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Pacemaker lead (INGEVITY+) implanted in the left bundle branch area
What this could lead to
If successful, this could confirm that pacing the left bundle branch area is a safe and effective way to treat slow heart rhythms while keeping the heart's natural pumping pattern.
What could go wrong
This is an observational study, not a randomized trial, so results may not prove superiority over standard pacing. Risks include lead dislodgement, infection, or ineffective pacing.

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Conditions

The condition(s) this trial relates to.

atrioventricular block Bradycardia bundle branch block, familial isolated complete right congestive heart failure progressive familial heart block, type 1A sick sinus syndrome sinoatrial node disorder syncope, familial vasovagal

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIOVENTRICULAR BLOCK BRADYCARDIA BUNDLE-BRANCH BLOCK SINUS NODE DYSFUNCTION

Contacts and locations

Locations

  • AOU Maggiore

    RECRUITING

    Novara, 28100, Italy

  • Azienda Ospedaliera Ospedale Niguarda Ca Granda

    NOT_YET_RECRUITING

    Milan, 20162, Italy

  • Azienda Ospedaliero-Universitaria di Ferrara-Hospital

    RECRUITING

    Ferrara, Emilia-Romagna, 44100, Italy

  • CHRU de Lille

    RECRUITING

    Lille, 59037, France

  • Clinique Saint-Pierre Ottignies-Hospital

    RECRUITING

    Brussels, 1340, Belgium

  • East Surrey Hospital

    RECRUITING

    Redhill, Surrey, RH1 5RH, United Kingdom

  • Hospital Clinico Universitario Lozano Blesa

    RECRUITING

    Zaragoza, 50009, Spain

  • Hospital Europeen Georges-Pompidou (HEGP)

    RECRUITING

    Paris, 75908, France

  • Inselspital Bern

    RECRUITING

    Bern, 3010, Switzerland

  • Marienhospital-Hospital

    RECRUITING

    Osnabrück, Lower Saxony, 49074, Germany

  • Saarland University Hospital

    NOT_YET_RECRUITING

    Homburg, Saarland, 66421, Germany

  • St. Jan-Hospital

    RECRUITING

    Bruges, 8000, Belgium

  • Virgen de las Nieves University Hospital

    RECRUITING

    Granada, 18014, Spain

    Contact Email: •••••@•••••

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