Could a pacemaker also treat high blood pressure? a new device aims to do both.

NCT ID NCT03757377

Terminated Disease control Sponsor: BackBeat Medical Inc Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests a special pacemaker called the Moderato System in people who need a pacemaker and have high blood pressure that is hard to control with medication. The device is implanted like a regular pacemaker and may help lower blood pressure by adjusting the heart's pacing. About 200 participants will be randomly assigned to have the blood-pressure-lowering feature turned on or off for 12 months, while continuing their usual blood pressure drugs. The study measures whether the device safely reduces average blood pressure over 24 hours.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BackBeat Moderato System (implantable device)
What this could lead to: If it works, this device could offer a new way to control blood pressure without extra drugs for people who already need a pacemaker.
What could go wrong: This is a mid-stage trial with 203 participants. The device is implanted and carries surgical risks, and the blood-pressure benefit may be modest or not last long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrioventricular block Hypertension Resistant to Conventional Therapy hypertensive disorder resistant hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIOVENTRICULAR BLOCK HYPERTENSION, RESISTANT TO CONVENTIONAL THERAPY

Contacts and locations

Locations

Samodzielnym Publicznym Centralnym Szpitalem Klinicznym

Warsaw, 02-097, Poland
Silesian Center for Heart Diseases

Zabrze, 41-800, Poland
UZ Brussel - Heart Rhythm Management Center

Brussels, 1090, Belgium
Vilnius University Hospital Santariskiu Klinikos

Vilnius, 08661, Lithuania

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