BRADYCARDIA

This study tests two ways to treat a slow heart rate caused by overactive nerves, without using a permanent pacemaker. One method uses freezing (cryoablation) and the other uses burning (radiofrequency) to calm the nerves. Sixty adults aged 18 to 60 with symptoms like fainting or…

This study is testing a new, wire-free pacemaker called LivIQ in 325 people who need a pacemaker for a slow heartbeat. The goal is to see if it is safe and works well to keep the heart beating at the right pace. Participants will be followed for several months to check the device…

This study is testing a pacemaker lead placed in a specific area of the heart called the left bundle branch area. The goal is to see if this placement is safe and helps the heart beat more naturally in people with slow heart rates. About 140 participants will get the lead and be …

This study follows 1,805 people who already have an Aveir DR leadless pacemaker to see how safe it is over 5 years. The pacemaker helps control slow heart rhythms without wires. Researchers will track complications shortly after implant and for years afterward using real-world da…

This study compares a new pacing method called conduction system pacing (CSP) to standard pacing for people with a slow heart rate and a wide QRS pattern on their ECG. The goal is to see if CSP better preserves the heart's pumping ability over one year. About 120 adults who need …

This study is testing a new type of heart pacing lead that is placed in the left bundle branch area, a key part of the heart's electrical system. The goal is to see if this approach is safe and works better than standard pacing for people with bradycardia (slow heart rate) or hea…

This study tests a new way to program pacemakers to help lower blood pressure in people who have both high blood pressure and a slow heart rate. About 30 adults who already have or need a special pacemaker will try two different setup sessions. Researchers will check if the new s…

This study compares two pacemaker methods for people with a slow heart rate: standard right ventricular pacing and a newer 'physiological pacing' that targets the heart's natural conduction system. Researchers will track 2,600 participants over time to see which method better pre…

This study tests a new type of electrocardiogram (UHF-ECG) that uses ultra-high frequency waves to detect when the heart's lower chambers are not beating in sync. Researchers will compare it to the standard 12-lead ECG in 360 adults with slow heart rate or heart failure who are s…

This study tests whether adjusting a pacemaker's lower heart rate to an individual's optimal level can improve symptoms and quality of life in people with heart failure and bradycardia. Researchers will compare this personalized approach to the standard fixed rate of 60 beats per…

This study compares three sedation approaches—using dexmedetomidine, propofol, or both—during cataract surgery in 1,000 adults. Researchers will measure how well each method sedates patients, affects heart rate and blood pressure, and causes side effects like nausea. The goal is …

This study compares two types of ultrasound-guided nerve blocks (supra-inguinal and infra-inguinal fascia iliaca blocks) in 60 adults aged 30-60 undergoing thigh or knee surgery. The goal is to see which block makes it easier for patients to get into position for spinal anesthesi…

This study compares two drugs, dexmedetomidine and dexamethasone, when added to a standard local anesthetic (ropivacaine) for a nerve block in the shoulder area. The goal is to see which combination provides faster pain relief for patients undergoing arm surgery. 66 adults aged 1…

This study compares two ultrasound-guided nerve blocks—supra-inguinal fascia iliaca block and pericapsular nerve group block—to see which one better reduces pain when positioning patients for spinal anesthesia during femur fracture surgery. Seventy adults with a broken femur will…

This study will observe 1000 people who receive BIOTRONIK pacemakers for conditions like slow heartbeat or heart failure. The goal is to see how well the devices work in everyday medical practice, focusing on safety and performance over time. Researchers will track device-related…

This study monitors how long Medtronic heart devices (like pacemakers) last and how often they have problems. It includes up to 20,000 people who have or will get one of these devices. The goal is to collect real-world data to improve future device safety and performance.

This study follows 1000 people with slow heart rates who already have a specific pacemaker. Researchers want to see if the pacemaker's data on sleep breathing and activity can predict future heart attacks, strokes, or irregular heartbeats. No new treatments are given—just observa…

This study looks at how a special pacing method called His bundle pacing affects the heart's electrical activity in 80 people with bradycardia (slow heart rate) or heart failure. Researchers will take extra measurements during standard pacemaker implantation to see if this techni…

This study tests a portable ECG system that helps doctors monitor the placement of a pacing lead in the heart during a pacemaker or similar device implantation. About 55 adults who need this procedure will take part. The goal is to see if the portable system works as well as stan…

This study looks at whether playing womb-like sounds to preterm infants can help their brains mature and control breathing more steadily. Researchers will monitor 34 babies born at 29-33 weeks for breathing pauses, low oxygen, and slow heart rate. The goal is to understand how ea…

This study watches how well a small heart monitor (BIOMONITOR III) works in routine medical care for 1400 people. It tracks how quickly the device finds hidden heart rhythm problems like atrial fibrillation or fainting spells. The goal is to learn about the device's real-life per…

This study looks at the electrical signals in the heart during a special type of pacing called left bundle branch area pacing (LBBAP), used in people with heart failure or slow heart rates. Researchers will measure these signals at different pacing strengths and body positions in…