Pacemaker tweak may also lower blood pressure

NCT ID NCT04463121

Completed Knowledge-focused Sponsor: BackBeat Medical Inc Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether special pacing signals from a pacemaker can improve heart function and lower blood pressure in people who need a pacemaker and also have high blood pressure. Researchers will measure heart pressure and volume using a thin catheter inside the heart. The goal is to see if these signals can help control blood pressure while treating a slow heart rate.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cardiac Neuromodulation Therapy (CNT) pacing signals delivered via a pacemaker device
What this could lead to: If successful, this could help develop a pacemaker-based treatment that lowers blood pressure while managing slow heart rate.
What could go wrong: This is a small, short-term study done just before a pacemaker implant, so results may not apply to long-term use or to broader patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BRADYCARDIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Bradycardia hypertensive disorder Isolated Systolic Hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRADYCARDIA HYPERTENSION, SYSTOLIC

Contacts and locations

Locations

Na Homolce Hospital

Prague, 15030, Czechia

More trials for these conditions

Other studies related to the condition(s) this trial covers.