Boston Scientific Corporation

This study tests whether a procedure called pulsed field ablation (PFA) is safer and more effective than anti-arrhythmic drugs as a first treatment for people with persistent atrial fibrillation (a type of irregular heartbeat). About 484 adults with symptomatic persistent AFib wi…

This study tests a new modular pacing system that works with an under-the-skin defibrillator to detect and stop dangerous heart rhythms. About 297 people with or at risk for ventricular tachycardia will get the system. The goal is to see if the devices can communicate and deliver…

This study tests a treatment called BSJ020R for people whose dialysis fistulas are narrowing or blocking up. The goal is to see if it can keep the fistula open longer without needing another procedure. About 186 adults with mature fistulas that have been working for at least two …

This study tests a special balloon coated with a drug (paclitaxel) to treat heart stents that have narrowed again after a previous procedure. About 20 adults with this condition will receive the balloon treatment or standard care. The goal is to see if the balloon is safe and eff…

This study compares two treatments for people with a serious type of blood clot in the lungs (pulmonary embolism). Half of the 544 participants will receive standard blood thinners, while the other half will get blood thinners plus a special device that uses ultrasound to help di…

This study tests a special balloon coated with a drug (paclitaxel) to treat heart arteries that have narrowed again after a stent was placed. About 600 adults with this condition will be randomly assigned to get either the drug-coated balloon or a standard balloon procedure. The …

This study follows 228 people with paroxysmal atrial fibrillation (a type of irregular heartbeat) who received a treatment called FARAPULSE pulsed field ablation. The goal is to see if the procedure is safe and effectively stops abnormal heart rhythms for at least a year. Partici…

This study compares two types of drug-coated balloon catheters to treat narrowed small arteries in the heart. About 180 adults with coronary artery disease will be randomly assigned to receive one of the two balloons. The goal is to see which device better prevents the need for r…

This study compares the WATCHMAN FLX device, which closes off a part of the heart to prevent clots, with standard blood thinners (NOACs) in 3,000 people with non-valvular atrial fibrillation. The goal is to see if the device is as good as medication at preventing stroke and death…

This study tested whether stimulating the vagus nerve in the neck could improve heart function in 118 people with advanced heart failure. Participants had a device implanted to deliver mild electrical pulses to the nerve. The goal was to see if this therapy could reduce heart siz…

This study is a registry that will follow about 450 men who receive a Boston Scientific penile implant to treat erectile dysfunction. Researchers will collect real-world data on how well the implant works and its safety over time. Participants will complete questionnaires about e…

This study compares a new treatment called TheraSphere (tiny radioactive beads) against standard chemoembolization for people with liver cancer that cannot be removed by surgery. About 92 Chinese adults with early-to-mid stage liver cancer will be randomly assigned to one of the …

This study tests a device that freezes small areas of heart tissue to treat a common type of irregular heartbeat called paroxysmal atrial fibrillation (AFib). About 200 people who have not responded to medication will receive this freezing treatment. The goal is to see if it is s…

This study tests a two-step treatment for liver cancer. First, tiny radioactive beads are injected into the liver to destroy tumors. Then, two immunotherapy drugs (durvalumab and tremelimumab) are given to help the immune system fight any remaining cancer. The goal is to see how …

This study collects information on the safety and effectiveness of a heart procedure for atrial fibrillation using the FARAPULSE system, which uses electrical pulses to treat abnormal heart rhythms. About 550 adults will be followed for one year after their standard-of-care ablat…

This study follows 166 people aged 45 and older who received the Superion implant to treat lumbar spinal stenosis, a condition that narrows the spine and causes leg and back pain. The goal is to see if the implant provides lasting symptom relief and reduces the need for additiona…

This study compares a minimally invasive water vapor treatment (REZŪM) to a two-drug combination for men with an enlarged prostate whose symptoms didn't improve with one drug. The goal is to see which approach better relieves urinary symptoms and preserves sexual function. About …

This study tests a new device called the Millipede Ring, which is placed inside the heart to help a leaky mitral valve close better. It is for people with moderate to severe functional mitral regurgitation who still have symptoms despite medication. The study involves only 4 part…

This trial tested a new device called ACURATE to replace a narrowed heart valve in nearly 2,000 people with severe aortic stenosis. The goal was to see if it was safe and effective compared to standard treatments. However, the company stopped the program in 2025 and will not seek…

This study follows over 1,100 people with atrial fibrillation who received a new treatment called FARAPULSE pulsed field ablation. The procedure uses electrical pulses to destroy tiny areas of heart tissue causing irregular rhythm. Researchers are watching for safety issues and h…

This study tests the safety of a device called TheraSphere for men with localized prostate cancer. It uses tiny radioactive beads to deliver radiation directly to the tumor. The goal is to find the highest safe dose and see what side effects occur. About 36 men will take part in …

This study tests whether people with atrial fibrillation can take just one blood thinner or aspirin after getting a WATCHMAN FLX Pro device, instead of the usual two-drug plan. About 1,857 participants will be followed for 6 months to see if the simpler plans are as safe and effe…

This study tests a gel called SpaceIT that is injected between the prostate and rectum before radiation therapy for prostate cancer. The gel creates space to reduce radiation reaching the rectum, aiming to prevent side effects. About 230 men with low- to intermediate-risk prostat…

This study tests whether spinal cord stimulation (SCS) can reduce chronic limb pain caused by diabetic peripheral neuropathy. About 28 adults with diabetes and long-lasting leg or foot pain will receive an SCS device and be followed for 12 months. The main goal is to see how much…

This study looks at whether a special stent (Hot AXIOS™) can improve quality of life for people with bile duct blockage caused by cancer, after standard drainage methods have failed. About 162 adults will be followed for two months after the stent is placed. The main goal is to s…

This study tests a spinal cord stimulator that delivers pain relief without the usual tingling sensation. It involves 177 adults with long-term back and limb pain. The goal is to see if this new therapy can cut pain by at least half within three months.

This study tests whether a gel called SpaceOAR Vue, placed between the prostate and the bowel, can reduce bowel side effects in men receiving high-dose radiation for prostate cancer. About 500 men with intermediate-risk prostate cancer will be randomly assigned to get radiation w…

This study tests a new way to place a stent (a small mesh tube) to open a stomach blockage caused by advanced cancer. The goal is to help people eat and drink more easily. About 67 adults who cannot have surgery will take part. Doctors will check if the stent is safe and works we…

This study planned to test a disposable duodenoscope (Exalt D) in up to 35 people undergoing ERCP, a procedure to examine the bile and pancreatic ducts. The goal was to see if the single-use scope could complete the procedure without switching to a reusable one. However, the stud…

This study looks at how doctors use the FARAPULSE system to treat atrial fibrillation (an irregular heartbeat) in real-world settings. Researchers will collect data from 524 patients to see which steps before, during, and after the procedure work best. The goal is to improve safe…

This study was designed to see if a new medical device could safely help drain bile from the liver in people with bile duct blockage caused by cancer. The device was meant to be used during a procedure called hepaticogastrostomy. However, the study was withdrawn before any partic…

This study tests whether using a tiny camera inside the pancreas during surgery can find hidden tumor spots that might otherwise be missed. About 100 people with a precancerous pancreas condition called IPMN will have the camera procedure during their planned surgery. The goal is…

This study looks at how well a specific heart stent (SYNERGY) works in everyday medical practice in China. About 2,000 people with heart disease who receive this stent will be followed to see how they do. The goal is to gather real-world information, not to test a new treatment.

This study is collecting information from small heart monitors placed under the skin of 525 people with heart failure. The goal is to learn how sensor data might relate to heart failure events like hospital visits. Participants have moderate heart failure and are not expected to …