Boston Scientific Corporation

This study tests whether a procedure called pulsed field ablation (PFA) is safer and more effective than anti-arrhythmic drugs as a first treatment for people with persistent atrial fibrillation, a type of irregular heartbeat. About 484 participants will be randomly assigned to r…

This study looks at how safe and effective a new treatment called FARAPULSE pulsed field ablation is for people with a type of irregular heartbeat called paroxysmal atrial fibrillation. About 228 participants will be followed for up to 12 months to see if the procedure stops the …

This study tests two treatments for people with intermediate-high risk pulmonary embolism (a serious blood clot in the lungs). Half receive standard blood thinners, and the other half get blood thinners plus a special ultrasound device that helps dissolve the clot. Researchers wi…

This study tests a device that electrically stimulates the vagus nerve to help manage heart failure. About 118 patients with moderate-to-severe heart failure received the implant. The goal is to see if this stimulation can improve heart function and exercise capacity over six mon…

This trial tests two types of drug-coated balloon catheters to treat small, newly blocked heart arteries. About 180 adults with stable or unstable angina will be randomly assigned to receive one of the two devices during a standard angioplasty procedure. The goal is to see which …

This study tests a new system that combines a leadless pacemaker with a subcutaneous defibrillator to treat dangerously fast heart rhythms. The devices communicate wirelessly to deliver pacing therapy without wires inside the heart. About 300 people at risk for ventricular tachyc…

This early study tests the safety of TheraSphere PCa, tiny radioactive glass beads injected into the prostate to treat localized prostate cancer. The trial involves 36 men with favorable intermediate-risk cancer and aims to find the maximum safe radiation dose. Researchers will m…

This study tests a two-step treatment for liver cancer. First, patients receive TheraSphere, tiny radioactive beads injected into the liver to target tumors. Then, they get two immunotherapy drugs (durvalumab and tremelimumab) to help the immune system fight remaining cancer cell…

This study is tracking over 1,100 people with atrial fibrillation who are treated with the FARAPULSE system, a device that uses electrical pulses to destroy tiny areas of heart tissue causing the irregular rhythm. The goal is to see how well it works and how safe it is in everyda…

This registry tracks 550 people with atrial fibrillation who are treated with the FARAPULSE pulsed field ablation system, using a special catheter and mapping technology. The goal is to see how safe and effective the procedure is in real-world settings over one year. Researchers …

This early study tested a new device called the Millipede ring, which is delivered through a catheter to tighten the mitral valve in people with functional mitral regurgitation (a leaky valve). Only 4 participants were enrolled to see if the procedure is safe and technically poss…

This study tests a special balloon coated with a drug to treat heart arteries that have narrowed again after a stent was placed. About 600 adults with this condition will be randomly assigned to receive either the drug-coated balloon or a standard balloon procedure. The goal is t…

This study tests a special balloon coated with the drug paclitaxel to treat in-stent restenosis, where a previously placed stent in a heart artery narrows again. Twenty adults who have this condition will receive the balloon treatment or standard care. Researchers will check if t…

This study tests whether people with atrial fibrillation who receive a WATCHMAN FLX Pro device can safely take just one blood thinner or aspirin instead of the usual two-drug plan. About 1,857 participants are being followed for six months to compare rates of death, stroke, major…

This large study is testing whether a device called WATCHMAN FLX, which closes off a small pouch in the heart, can be a safe and effective alternative to daily blood thinners (NOACs) for preventing strokes in people with non-valvular atrial fibrillation. The trial involves 3,000 …

This study is a registry that collects real-world information on the safety and effectiveness of Boston Scientific penile implants for erectile dysfunction. It will enroll 450 men who are already scheduled to receive the implant. Researchers will track changes in erectile functio…

This study tests a gel called SpaceIT that is placed between the prostate and rectum before radiation therapy for prostate cancer. The gel acts as a spacer to reduce radiation reaching the rectum, potentially lowering side effects. About 230 adults with low- to intermediate-risk …

This study compares a minimally invasive water vapor treatment (REZŪM) to taking two drugs together for men with an enlarged prostate that didn't get better with one drug. It includes 155 sexually active men aged 45 and older. The goal is to see which approach better improves uri…

This study compares a new treatment called TheraSphere (tiny radioactive beads) to standard chemoembolization for people with liver cancer that cannot be removed by surgery. About 92 Chinese adults with early-to-mid stage liver cancer will be randomly assigned to one of the two t…

This study tests a special balloon coated with the drug paclitaxel to treat blockages in arm fistulas used for dialysis. The balloon is inflated to open the narrowed blood vessel and release the drug to help keep it open. Researchers will check if the fistula stays open without n…

This study tested a new device called the ACURATE neo2, which replaces a narrowed heart valve without open-heart surgery. About 1,900 people with severe aortic stenosis received either the new device or a standard one. The goal was to see if the new device is safe and works as we…

This study was designed to test a new device for accessing the bile duct in patients with bile duct blockages caused by cancer. The goal was to see if the device could safely and effectively help drain the bile. However, the study was withdrawn before any patients were enrolled, …

This study looks at whether a special stent (Hot AXIOS) can improve quality of life for people with bile duct blockages caused by cancer, when standard drainage fails. About 162 adults will receive the stent during an endoscopic procedure. The main goal is to see if jaundice symp…

This trial tests a biodegradable gel called SpaceOAR Vue that is injected between the prostate and rectum before radiation therapy. The gel temporarily pushes the rectum away to reduce radiation damage. About 500 men with intermediate-risk prostate cancer will be randomly assigne…

This study tests a spinal cord stimulator that delivers fast-acting pain relief without the usual tingling sensation. About 177 adults with long-term back and limb pain will use the device. The main goal is to see if at least half of them get 50% or more pain reduction after 3 mo…

This study tests a special stent placed using an endoscope to connect the stomach to the small intestine in people whose stomach is blocked by advanced cancer. The goal is to help them eat and drink more easily without major surgery. The study plans to enroll 67 participants and …

This study follows 166 people aged 45 and older who received the Superion IDS implant for lumbar spinal stenosis, a condition that narrows the spine and causes leg pain. The implant is designed to limit certain movements that worsen symptoms. Researchers are checking if patients …

This study follows 2,000 people in China who received the SYNERGY stent to open blocked heart arteries. Researchers are collecting real-world data on safety and major heart events after the procedure. The goal is to see how well the stent performs in everyday medical practice.

This registry is collecting data from over 500 patients with atrial fibrillation who are treated with the FARAPULSE ablation system in routine care. The goal is to identify which pre-procedure, procedure, and follow-up steps work best for different types of patients. Researchers …

This study is testing an implantable heart monitor (LUX-Dx ICM) in 525 people with heart failure. The goal is to collect sensor data to better understand when heart failure events happen. Participants have moderate heart failure (NYHA class II or III) and certain heart structure …

This study tests a tiny camera called SpyGlass that doctors insert into the pancreatic duct during surgery for a condition called IPMN (a type of cyst that can turn into cancer). The goal is to see if the camera can find small, hidden tumors that standard scans miss. About 100 pa…

This study looked at how well a single-use duodenoscope (called Exalt D) works for ERCP procedures in China. The goal was to see if it could complete the procedure without needing a reusable scope. Up to 35 adults scheduled for ERCP were planned to take part, but the study was wi…