Wireless heart pacemaker and defibrillator team up to stop dangerous rhythms

NCT ID NCT04798768

Ongoing Disease control Sponsor: Boston Scientific Corporation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study tests a new system that combines a leadless pacemaker with a subcutaneous defibrillator to treat dangerously fast heart rhythms. The devices communicate wirelessly to deliver pacing therapy without wires inside the heart. About 300 people at risk for ventricular tachycardia are enrolled to see if the system is safe and works well in different body positions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: EMPOWER modular pacing system and EMBLEM subcutaneous ICD
What this could lead to: If successful, this could offer a less invasive, wire-free way to treat dangerous heart rhythms and reduce the need for repeat procedures.
What could go wrong: This is an early-stage device trial with a moderate number of participants. The system may fail to communicate properly or cause complications like infection or device malfunction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Arrhythmias, Cardiac cardiac rhythm disease ventricular fibrillation ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARRHYTHMIA, VENTRICULAR TACHYCARDIA, VENTRICULAR

Contacts and locations

Locations

AZ Osp Monaldi

Naples, 80131, Italy
AdventHealth Orlando

Orlando, Florida, 32803, United States
Amsterdam University Medical Center

Amsterdam, Netherlands
Arrhythmia Research Group

Jonesboro, Arkansas, 72401, United States
Azienda Ospedaliero Universitaria Pisana

Pisa, 56126, Italy
Banner University Medical Center Phoenix

Phoenix, Arizona, 85006, United States
Baptist Health Lexington

Lexington, Kentucky, 40503, United States
CHRU de Lille

Lille, 59000, France
CHU Grenoble - Hospital Michallon

Grenoble, France
CHU de Nantes-Hopital Laennec

Nantes, France
Cleveland Clinic

Cleveland, Ohio, 44195, United States
Cooper Hospital - University Medical Center

Camden, New Jersey, 08103, United States
Emory University Hospital

Atlanta, Georgia, 30308, United States
Erasmus MC University Medical Center

Rotterdam, 3015 CE, Netherlands
Erlanger Medical Center

Chattanooga, Tennessee, 37403, United States
Hospital Clinic of Barcelona

Barcelona, 08036, Spain
Hospital European Georges-Pompidou

Paris, France
Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
Institut Universitaire de Cardilogie et Pnuemologie de Quebec (IUCPQ)

Québec, Canada
Institut de Cardiologie de Quebec (Montreal Heart)

Montreal, Quebec, H1T 1C8, Canada
Kepler Universitaetsklinikum

Linz, Austria
Liverpool Heart and Chest Hospital

Liverpool, L14 3PE, United Kingdom
Manchester Heart Center

Manchester, M13 9WL, United Kingdom
Maria Cecilia Hospital SPA

Cotignola, Italy
Mayo Clinic

Rochester, Minnesota, 55905, United States
Mount Sinai Medical Center

New York, New York, 10029, United States
Na Homolce Hospital

Prague, Czechia
Northwell University Hospital

Manhasset, New York, 11030, United States
Ohio Health Research Institute

Columbus, Ohio, 43214, United States
Ohio State University Medical Center

Columbus, Ohio, 43210, United States
Penn State Health Milton S. Hershey Medical Center

Hershey, Pennsylvania, 17033, United States
Scottsdale Healthcare - Shea

Scottsdale, Arizona, 84258, United States
Sentara Norfolk General

Norfolk, Virginia, 23507, United States
Southampton University Hospital

Southampton, United Kingdom
Spedali Civil di Brescia

Brescia, Italy
St. Antonius Ziekenhuis

Nieuwegein, Netherlands
The General Infirmary

Leeds, LS1 EX, United Kingdom
University of Washington Medical Center

Seattle, Washington, 98195, United States

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