Tiny ring could fix leaky heart valve without open surgery
NCT ID NCT04147884
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tested a new device called the Millipede ring, which is delivered through a catheter to tighten the mitral valve in people with functional mitral regurgitation (a leaky valve). Only 4 participants were enrolled to see if the procedure is safe and technically possible. The goal is to offer a less invasive alternative to open-heart surgery for heart failure patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Millipede Transcatheter Annuloplasty Ring System (a repair device implanted via catheter to tighten the mitral valve)
What this could lead to
If successful, this device could offer a less invasive way to fix leaky mitral valves, potentially reducing heart failure symptoms and avoiding open-heart surgery.
What could go wrong
This is a very early feasibility study with only 4 participants, so results may not apply broadly. The device could cause serious complications like stroke, bleeding, or valve damage.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Columbia University Medical Center/New York Presbyterian Hospital
New York, New York, 10032, United States
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Monash Health
Clayton, Victoria, 3168, Australia
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Montefiore Medical Center
The Bronx, New York, 10467, United States
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Tucson Medical Center Healthcare
Tucson, Arizona, 85712, United States