Tiny ring could fix leaky heart valve without open surgery

NCT ID NCT04147884

Ongoing Disease control Sponsor: Boston Scientific Corporation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times

Summary

This early study tested a new device called the Millipede ring, which is delivered through a catheter to tighten the mitral valve in people with functional mitral regurgitation (a leaky valve). Only 4 participants were enrolled to see if the procedure is safe and technically possible. The goal is to offer a less invasive alternative to open-heart surgery for heart failure patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Millipede Transcatheter Annuloplasty Ring System (a repair device implanted via catheter to tighten the mitral valve)
What this could lead to: If successful, this device could offer a less invasive way to fix leaky mitral valves, potentially reducing heart failure symptoms and avoiding open-heart surgery.
What could go wrong: This is a very early feasibility study with only 4 participants, so results may not apply broadly. The device could cause serious complications like stroke, bleeding, or valve damage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder mitral valve disorder mitral valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASES MITRAL REGURGITATION FUNCTIONAL MITRAL VALVE DISEASE

Contacts and locations

Locations

Columbia University Medical Center/New York Presbyterian Hospital

New York, New York, 10032, United States
Monash Health

Clayton, Victoria, 3168, Australia
Montefiore Medical Center

The Bronx, New York, 10467, United States
Tucson Medical Center Healthcare

Tucson, Arizona, 85712, United States

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