MITRAL VALVE DISEASE

This study is testing a new type of biological heart valve that features an 'easy change' system, designed to make future replacements simpler. Researchers will implant these valves in 500 people with aortic valve disease and track complications like blood clots, infections, and …

This early-stage study tests a new device called the ReValve system to replace the mitral valve in people with severe valve leakage. About 25 adults with symptoms like shortness of breath will get the device to see if it can be delivered safely and works as intended. The goal is …

This study is testing a new way to replace a damaged heart valve (the mitral valve) without open-heart surgery. It uses a special valve delivered through a thin tube (catheter) for people with severe symptoms who are not healthy enough for standard surgery. The study will enroll …

This study is testing a new artificial heart valve (MITRIS RESILIA) in 250 Chinese patients who need their mitral valve replaced. The goal is to see how safe and well the valve works over time by measuring blood flow and leaks. Participants must be 18 or older and willing to foll…

This study tests a device called CoolCryo that freezes small areas of heart tissue to stop atrial fibrillation (an irregular heartbeat). It is being used in 20 people who are already having mitral valve surgery. The goal is to see if the freezing treatment can keep the heart in n…

This study looks at whether a special 3D ultrasound technique called TrueVue can better find and measure calcium buildup on the mitral valve, a common heart problem. Researchers will compare the ultrasound images to CT scans in 100 adults who already need these tests. If successf…

This early-phase study tests whether placing amiodarone directly into the sac around the heart during open-chest surgery can prevent a common and serious irregular heartbeat called atrial fibrillation. About 63 adults aged 20-85 having bypass or valve surgery will receive this tr…

This study tests whether watching an AI-made video before and after mitral valve repair surgery can reduce unplanned calls, emails, or visits to the doctor. About 100 adults scheduled for this heart surgery will be randomly assigned to receive the video or standard instructions. …

This study is a registry that collects information from 1,000 people with symptomatic mitral valve disease, including mitral regurgitation and stenosis. The goal is to better understand how correcting these heart valve problems with a less invasive procedure called transcatheter …

This study follows 500 adults with severe mitral valve disease who are not candidates for surgery. Researchers will track deaths and heart-related hospitalizations over two years to understand how these patients fare. The goal is to gather real-world data to help doctors make bet…

This registry is following 1,000 patients with a leaky mitral valve (mitral regurgitation) who undergo a minimally invasive procedure called transcatheter mitral valve replacement (TMVR). The goal is to see how well the procedure works in everyday medical practice, including how …

This study is looking at how well the Mosaic mitral heart valve works over time in people under 65. Researchers will review medical records of 300 patients who had this valve placed at ProMedica Toledo Hospital. The goal is to understand survival rates, valve stability, and the n…

This study is following 10,000 adults with heart valve disease to see how their condition changes over time. Researchers will use scans, blood tests, and health records to track progression and the effects of treatments like surgery or medication. The goal is to better predict ou…

This study uses artificial intelligence to analyze data from 21,000 patients who had heart valve procedures. The goal is to make AI tools that can predict surgery outcomes, like which device to use and risks of complications, with over 90% accuracy. This is a non-interventional s…