New heart valve design aims to simplify replacements and cut risks
NCT ID NCT04442100
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing a new type of biological heart valve that features an 'easy change' system, designed to make future replacements simpler. Researchers will implant these valves in 500 people with aortic valve disease and track complications like blood clots, infections, and valve wear over time. The goal is to see if the new design improves safety and outcomes compared to standard valves.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
biological prosthetic heart valves (MedEng-Bio)
What this could lead to
If successful, this could make heart valve replacements easier to perform and reduce serious complications like blood clots or infections.
What could go wrong
This is an early study without a control group, so results may not prove the new valve is better than existing options. Risks include typical surgery complications like bleeding or valve failure over time.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Tomsk National Research Medical Center of the Russian Academy of Sciences
RECRUITINGTomsk, Tomsk Oblast, 634012, Russia
Contact
Contact Email: •••••@•••••
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