10,000 patients join quest to unlock heart valve disease secrets

NCT ID NCT07267117

Recruiting now Knowledge-focused Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is following 10,000 adults with heart valve disease to see how their condition changes over time. Researchers will use scans, blood tests, and health records to track progression and the effects of treatments like surgery or medication. The goal is to better predict outcomes and improve care for people with valve problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better predict how heart valve disease will progress and guide decisions on treatments like surgery or lifestyle changes.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly test a new therapy. Results may take years and might not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Aortic Valve Disease aortic valve disorder aortic valve insufficiency aortic valve stenosis gastroesophageal reflux disease heart valve disorder mitral valve disorder mitral valve insufficiency mitral valve stenosis pulmonary valve disorder pulmonary valve insufficiency pulmonary valve stenosis tricuspid valve disorder tricuspid valve insufficiency tricuspid valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC VALVE DISEASE AORTIC VALVE REGURGITATION AORTIC VALVE STENOSIS HEART VALVE DISEASE MITRAL VALVE (MV) REGURGITATION MITRAL VALVE DISEASE MITRAL VALVE STENOSIS PULMONARY VALVE DISEASE TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR) TRANSCATHETER EDGE-TO-EDGE REPAIR TRANSCATHETER PULMONARY VALVE REPLACEMENT (TPVR) TRANSCATHETER VALVE REPLACEMENT TRICUSPID VALVE DISEASE TRICUSPID VALVE REGURGITATION

Contacts and locations

Locations

Affiliated Hospital of Qingdao University
RECRUITING

Qingdao, Shandong, 266000, China
Army Medical Center of PLA
RECRUITING

Chongqing, 400010, China
Chinese Academy of Medical Sciences, Fuwai Hospital
RECRUITING

Beijing, China
Fujian Provincial Hospital, Affiliated to Fuzhou University
RECRUITING

Fuzhou, Fujian, China
Fuwai Yunnan Cardiovascular Hospital
RECRUITING

Kunming, Yunnan, 650032, China
Huaxi Hospital
RECRUITING

Chengdu, Sichuan, China
Navy General Hospital, Beijing
RECRUITING

Beijing, China
People's Hospital of Xinjiang Uygur Autonomous Region
RECRUITING

Ürümqi, Xinjiang, 830000, China
Renmin Hospital of Wuhan University
RECRUITING

Wuhan, Hubei, 430060, China
Second Affiliated Hospital of Zhejiang University, School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310000, China
Second Xiangya Hospital of Central South University
RECRUITING

Changsha, Hunan, China
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
RECRUITING

Shanghai, 200080, China
The First Affiliated Hospital of Air Force Medicial University
RECRUITING

Xi'an, Shaanxi, 710032, China
The General Hospital of Northern Theater Command
RECRUITING

Shenyang, Liaoning, 110031, China
Xiangya Hospital of Central South University
RECRUITING

Changsha, Hunan, 410008, China

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