Can a tiny implant fix a leaky heart valve without open surgery?

NCT ID NCT07757698

Not yet recruiting Disease control Sponsor: Polares Medical SA Source: ClinicalTrials.gov ↗

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This study tests a new device called MRace, designed to repair a leaky mitral valve in the heart without open surgery. The device is placed through a vein in the leg and guided to the heart to help the valve close properly. The trial will include up to 15 people with severe mitral regurgitation and complex valve anatomy, and will follow them for five years to see if the device is safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: MRace Implant, a device for transcatheter mitral valve repair
What this could lead to: If successful, this could provide a new, less invasive treatment option for people with severe mitral regurgitation who have complex valve anatomy, potentially improving symptoms and quality of life.
What could go wrong: This is a small pilot study with only 15 patients, so results may not apply to everyone. The procedure carries risks like any heart intervention, and the device may not work as hoped in all cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gastroesophageal reflux disease mitral valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MITRAL VALVE (MV) REGURGITATION

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Other studies related to the condition(s) this trial covers.