Can a heart procedure cut stroke risk after valve repair? new trial aims to find out

NCT ID NCT07380932

Not yet recruiting Disease control Sponsor: Atrial Fibrillation Network Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at people with atrial fibrillation (an irregular heartbeat) who have already had a successful mitral valve repair. It compares two approaches: catheter ablation (a procedure to fix the heart's electrical signals) versus standard medical care. The goal is to see if ablation reduces major problems like stroke, heart failure, or death. About 956 participants will be randomly assigned to one of the two groups and followed over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: catheter ablation
What this could lead to: If successful, this could show that catheter ablation reduces the risk of heart failure, stroke, and death in patients with atrial fibrillation after mitral valve repair.
What could go wrong: This trial has not started recruiting yet, and it is an early-stage strategy comparison. The procedure carries risks like bleeding, infection, or heart rhythm problems, and may not prove superior to standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation gastroesophageal reflux disease mitral valve insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION (AF) MITRAL VALVE (MV) REGURGITATION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Asklepios Hospital St. Georg

Hamburg, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
University Heart and Vascular Center Frankfurt

Frankfurt, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
University Hospital Cologne

Cologne, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••
University Hospital Münster

Münster, 48149, Germany

Contact Phone: •••-•••-•••• Email: •••••@•••••

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