Can a tiny implant fix complex heart valve leaks without open surgery?
NCT ID NCT07757776
First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time
Summary
This study tests a new device called MRace, designed to repair severe mitral regurgitation—a condition where the heart's mitral valve doesn't close properly, causing blood to leak backward. The device is implanted through a vein in the leg, avoiding open-heart surgery, and is aimed at patients with complex valve anatomy that may be difficult to treat with standard methods. The trial will enroll up to 20 people in Germany and follow them for five years to see if the device safely reduces the leak and improves symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- MRace Implant and Delivery System (transcatheter mitral valve repair device)
- What this could lead to
- If successful, this could offer a new, less invasive treatment option for people with severe mitral regurgitation who have complex heart anatomy, potentially improving symptoms and quality of life.
- What could go wrong
- This is a small pilot study with only 20 patients, so results may not apply broadly. The procedure carries risks like bleeding, infection, or device-related complications, and long-term benefits are not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Other studies related to the condition(s) this trial covers.
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