AORTIC VALVE REGURGITATION
Clinical trials for AORTIC VALVE REGURGITATION explained in plain language.
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New valve device could fix leaky heart valve without open surgery
Disease control Recruiting nowThis study is testing a new device called the J-Valve, which is a replacement heart valve delivered through a tube in the leg, to treat severe aortic regurgitation (a leaky heart valve). The trial will include 194 people with severe symptoms who are at high risk for open-heart su…
Matched conditions: AORTIC VALVE REGURGITATION
Phase: NA • Sponsor: JC Medical, Inc., an affiliate of Edwards Lifesciences LLC • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Should you fix a leaky heart valve early? new study seeks answers
Disease control Recruiting nowThis study looks at whether early surgery to repair or replace the aortic valve is better than waiting until symptoms appear in people with severe aortic regurgitation (a leaky heart valve). About 217 adults with no symptoms but severe valve leakage will be randomly assigned to e…
Matched conditions: AORTIC VALVE REGURGITATION
Phase: NA • Sponsor: Na Homolce Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Virtual reality and scents could replace opioids for surgery pain
Symptom relief Recruiting nowThis study tests whether combining virtual reality with pleasant smells can lower pain and anxiety in people recovering from heart or lung surgery. About 80 adults scheduled for cardiothoracic surgery will either receive the VR-and-scent therapy or standard care. The goal is to s…
Matched conditions: AORTIC VALVE REGURGITATION
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Heart valve showdown: which measurement method wins for TAVR patients?
Knowledge-focused Recruiting nowThis study compares two methods—ultrasound (echocardiography) versus direct pressure measurements (catheterization)—to guide additional balloon inflation after valve-in-valve TAVR. About 310 people with failing surgical aortic valves will be randomly assigned to one method. The g…
Matched conditions: AORTIC VALVE REGURGITATION
Phase: NA • Sponsor: Institut universitaire de cardiologie et de pneumologie de Québec, University Laval • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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10,000 patients join quest to unlock heart valve disease secrets
Knowledge-focused Recruiting nowThis study is following 10,000 adults with heart valve disease to see how their condition changes over time. Researchers will use scans, blood tests, and health records to track progression and the effects of treatments like surgery or medication. The goal is to better predict ou…
Matched conditions: AORTIC VALVE REGURGITATION
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC