TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR)
Clinical trials for TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR) explained in plain language.
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New heart valve under 10-Year watch: will it last?
Disease control Recruiting nowThis registry will follow 500 adults with severe aortic stenosis who receive a SAPIEN 3 Ultra Resilia heart valve through a minimally invasive procedure. Researchers will track how well the valve works and how safe it is over 10 years. The goal is to see if this newer valve desig…
Matched conditions: TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR)
Sponsor: Institut für Pharmakologie und Präventive Medizin • Aim: Disease control
Last updated Aug 01, 2026 00:00 UTC
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Can a single antiplatelet drug beat aspirin after heart valve replacement?
Disease control Recruiting nowThis trial compares two single antiplatelet therapies—ticagrelor versus aspirin—in people who have just undergone transcatheter aortic valve implantation (TAVI) for severe aortic stenosis. The goal is to see which drug better prevents serious complications like stroke, heart atta…
Matched conditions: TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR)
Phase: PHASE4 • Sponsor: Fundacin Biomedica Galicia Sur • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Brain catcher: new device may prevent stroke during heart procedure
Disease control Recruiting nowThis study tests a new device called CHORDS that catches loose debris during a heart valve replacement procedure (TAVR). The debris can travel to the brain and cause a stroke. The trial will compare CHORDS to an existing device in 240 people with severe aortic stenosis. Participa…
Matched conditions: TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR)
Phase: NA • Sponsor: Resonova (Shanghai) Medtech Limited • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New heart valve procedure could help patients with leaky aortic valve
Disease control Recruiting nowThis study tests a new way to replace the aortic valve in people with severe aortic regurgitation (a leaky heart valve). About 180 patients will get either the new VitaFlow valve or another device through a tube in the leg. The goal is to see if the new valve is safe and effectiv…
Matched conditions: TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR)
Phase: PHASE4 • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Which sedation is best for TAVR recovery? new study aims to find out
Symptom relief Recruiting nowThis study tests whether the type of sedation given during a minimally invasive heart valve replacement (TAVR) affects how well patients recover the next day. 126 adults will be randomly assigned to receive propofol, dexmedetomidine, or midazolam with fentanyl during their proced…
Matched conditions: TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR)
Phase: PHASE4 • Sponsor: David Lyubashevsky • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Acupuncture before heart surgery may prevent blood pressure drops
Symptom relief Recruiting nowThis study tests whether applying mild electrical stimulation to specific acupoints before anesthesia can help maintain stable blood pressure during TAVR heart valve surgery. Researchers will compare two different stimulation frequencies in 150 adults aged 60 and older. The goal …
Matched conditions: TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR)
Phase: NA • Sponsor: Air Force Military Medical University, China • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Massive asian TAVR registry aims to unlock secrets of long-term valve success.
Knowledge-focused Recruiting nowThis study is a large registry that collects data from thousands of patients across Asia who have undergone transcatheter aortic valve replacement (TAVR) for severe aortic stenosis. Researchers will analyze medical records to see how well the valves perform over time and what fac…
Matched conditions: TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR)
Sponsor: Eunpyeong St. Mary's Hospital • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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New MRI technique could transform heart failure diagnosis
Knowledge-focused Recruiting nowThis study is testing a new way to use MRI scans to measure how well the heart's main pumping chamber works in people with severe aortic stenosis who are scheduled for valve replacement. Researchers will develop computer models to automatically analyze heart images and compare th…
Matched conditions: TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR)
Phase: NA • Sponsor: IRCCS Policlinico S. Donato • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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10,000 patients join quest to unlock heart valve disease secrets
Knowledge-focused Recruiting nowThis study is following 10,000 adults with heart valve disease to see how their condition changes over time. Researchers will use scans, blood tests, and health records to track progression and the effects of treatments like surgery or medication. The goal is to better predict ou…
Matched conditions: TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR)
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC