Which sedation is best for TAVR recovery? new study aims to find out

NCT ID NCT07556523

Recruiting now Symptom relief Sponsor: David Lyubashevsky Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether the type of sedation given during a minimally invasive heart valve replacement (TAVR) affects how well patients recover the next day. 126 adults will be randomly assigned to receive propofol, dexmedetomidine, or midazolam with fentanyl during their procedure. They will complete surveys about pain, comfort, and satisfaction on days 1 and 7 after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Propofol, Dexmedetomidine, or Midazolam with Fentanyl
What this could lead to: If it works, this could help doctors choose the best sedation for faster, more comfortable recovery after TAVR.
What could go wrong: This is a small, early-phase study comparing common drugs, so differences may be small or not apply to all patients. No new drug is being tested.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC VALVE STENOSIS TRANSCATHETER AORTIC VALVE REPLACEMENT (TAVR)

Contacts and locations

Locations

Endeavor Health
RECRUITING

Glenview, Illinois, 60026, United States

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