Heart surgery patients may get new shield against dangerous rhythm

NCT ID NCT06063538

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests whether placing amiodarone directly into the sac around the heart during open-chest surgery can prevent a common and serious irregular heartbeat called atrial fibrillation. About 63 adults aged 20-85 having bypass or valve surgery will receive this treatment. The goal is to see if this approach reduces hospital complications and extra time in the ICU.

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Conditions

The condition(s) this trial relates to.

aneurysm or dilatation of ascending aorta aortic valve disorder coronary artery disorder mitral valve disorder Postoperative Complications tricuspid valve disorder atrial fibrillation prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••