MITRAL VALVE DISEASE
Clinical trials for MITRAL VALVE DISEASE explained in plain language.
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New heart valve technology put to the test in 777 patients
Disease control CompletedThis study tested whether a new way of processing tissue for Edwards heart valves is safe and works well. 777 adults who needed a new aortic or mitral valve took part. Researchers checked for valve problems like wear or calcification over about a year, and will follow patients fo…
Matched conditions: MITRAL VALVE DISEASE
Phase: NA • Sponsor: Edwards Lifesciences • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Nerve block before heart surgery may shield muscle from damage
Disease control CompletedThis study tested whether a left stellate ganglion block, given before mitral valve replacement, could protect the heart muscle. 62 adults undergoing elective on-pump mitral valve replacement received either a saline placebo or bupivacaine nerve block. Researchers checked for mic…
Matched conditions: MITRAL VALVE DISEASE
Phase: NA • Sponsor: Minia University • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Oxygen-Guided transfusions may cut unnecessary blood use in heart surgery
Disease control CompletedThis study tested whether using a measure of oxygen in the blood (SvO2) to guide red blood cell transfusions during heart surgery could reduce how many patients receive transfusions. Over 600 adults undergoing on-pump cardiac surgery were randomly assigned to either standard rest…
Matched conditions: MITRAL VALVE DISEASE
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Which workout helps heart surgery patients recover faster?
Symptom relief CompletedThis study looked at two types of exercise training—moderate-intensity interval training and continuous training—in 56 adults aged 40-60 who had mitral valve replacement surgery 4-8 weeks earlier. Over 12 weeks, researchers measured walking ability, lung function, heart efficienc…
Matched conditions: MITRAL VALVE DISEASE
Phase: NA • Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Gum treatment before heart surgery may save lives, study hints
Knowledge-focused CompletedThis study looked back at records of 200 adults who had heart valve surgery to see if treating gum disease beforehand lowered their risk of infection or death after the operation. Researchers checked dental X-rays and medical charts from 2015 to 2024. The goal is to understand if…
Matched conditions: MITRAL VALVE DISEASE
Sponsor: Istanbul University - Cerrahpasa • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Heart ultrasound during surgery may predict dangerous complication
Knowledge-focused CompletedThis study looked at 140 adults having mitral valve surgery to see if a special heart ultrasound measure (called global longitudinal strain) could predict a serious complication called low cardiac output syndrome. Researchers checked ultrasound images taken during surgery and tra…
Matched conditions: MITRAL VALVE DISEASE
Sponsor: Scientific Institute San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Robot Knot-Tier tested in heart surgery
Knowledge-focused CompletedThis study collected information from multiple hospitals on the Cor-Knot® device, which automatically ties knots during heart valve surgery. The goal was to see how safe and effective it is. Over 550 adults having planned valve surgery took part. The main focus was on whether lea…
Matched conditions: MITRAL VALVE DISEASE
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Heart valve showdown: which type lasts longer in patients under 70?
Knowledge-focused CompletedThis study looked at over 3,500 patients aged 70 or younger who had mitral valve replacement surgery in Austria between 2010 and 2020. Researchers compared those who got a mechanical valve versus a biological valve to see which group lived longer and needed fewer repeat operation…
Matched conditions: MITRAL VALVE DISEASE
Sponsor: Alissa Florian • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:37 UTC