Nerve block before heart surgery may shield muscle from damage
NCT ID NCT06476925
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a left stellate ganglion block, given before mitral valve replacement, could protect the heart muscle. 62 adults undergoing elective on-pump mitral valve replacement received either a saline placebo or bupivacaine nerve block. Researchers checked for microscopic heart muscle injury, arrhythmias, and troponin levels. The goal is to see if this simple procedure can reduce damage and improve recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bupivacaine
What this could lead to
If it works, this could lead to a simple procedure that reduces heart muscle damage and irregular heartbeats after mitral valve replacement.
What could go wrong
This is a small, single-center study with only 62 participants. The results may not apply to all heart surgery patients, and nerve blocks carry risks like bleeding or infection.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Mina Raouf
Minya, Minya Governorate, 61511, Egypt