New balloon treatment aims to clear blocked stents without extra surgery

NCT ID NCT06492174

Ongoing Disease control Sponsor: Boston Scientific Corporation Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 17, 2026 · Updated 3 times

Summary

This study tests a special balloon coated with the drug paclitaxel to treat in-stent restenosis, where a previously placed stent in a heart artery narrows again. Twenty adults who have this condition will receive the balloon treatment or standard care. Researchers will check if the balloon safely keeps the artery open and reduces the need for further procedures over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: paclitaxel-coated balloon catheter
What this could lead to: If successful, this could provide a new treatment option for people whose stented arteries narrow again, potentially reducing the need for repeat procedures.
What could go wrong: This is a small early-phase trial with only 20 participants, so results may not apply to everyone. The drug coating may cause side effects or not work better than existing options.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary restenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IN STENT RESTENOSIS

Contacts and locations

Locations

Baylor Heart and Vascular Hospital

Dallas, Texas, 75226, United States
Carondelet Medical Group St. Mary's Hospital

Tucson, Arizona, 85745, United States
Cedars Sinai Medical Center

Los Angeles, California, 90048, United States
Centennial Medical Center

Nashville, Tennessee, 37203, United States
Columbia University Medical Center

New York, New York, 10032, United States
Emory University Hospital

Atlanta, Georgia, 30322, United States
Henry Ford Hospital

Detroit, Michigan, 48202, United States
Lindner Center for Research and Education at Christ Hospital

Cincinnati, Ohio, 45219, United States
Rhode Island Hospital

Providence, Rhode Island, 02903, United States
St. Francis Hospital

Roslyn, New York, 11576, United States
UPMC Pinnacle Health

Wormleysburg, Pennsylvania, 17053, United States

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