New balloon treatment aims to clear blocked stents without extra surgery

NCT ID NCT06492174

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a special balloon coated with the drug paclitaxel to treat in-stent restenosis, where a previously placed stent in a heart artery narrows again. Twenty adults who have this condition will receive the balloon treatment or standard care. Researchers will check if the balloon safely keeps the artery open and reduces the need for further procedures over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

paclitaxel-coated balloon catheter

What this could lead to

If successful, this could provide a new treatment option for people whose stented arteries narrow again, potentially reducing the need for repeat procedures.

What could go wrong

This is a small early-phase trial with only 20 participants, so results may not apply to everyone. The drug coating may cause side effects or not work better than existing options.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary restenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor Heart and Vascular Hospital

    Dallas, Texas, 75226, United States

  • Carondelet Medical Group St. Mary's Hospital

    Tucson, Arizona, 85745, United States

  • Cedars Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Centennial Medical Center

    Nashville, Tennessee, 37203, United States

  • Columbia University Medical Center

    New York, New York, 10032, United States

  • Emory University Hospital

    Atlanta, Georgia, 30322, United States

  • Henry Ford Hospital

    Detroit, Michigan, 48202, United States

  • Lindner Center for Research and Education at Christ Hospital

    Cincinnati, Ohio, 45219, United States

  • Rhode Island Hospital

    Providence, Rhode Island, 02903, United States

  • St. Francis Hospital

    Roslyn, New York, 11576, United States

  • UPMC Pinnacle Health

    Wormleysburg, Pennsylvania, 17053, United States